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TBC31_BOVIN
ID   TBC31_BOVIN             Reviewed;        1063 AA.
AC   Q29RL0;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=TBC1 domain family member 31;
DE   AltName: Full=WD repeat-containing protein 67;
GN   Name=TBC1D31; Synonyms=WDR67;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC114127; AAI14128.1; -; mRNA.
DR   RefSeq; NP_001039538.1; NM_001046073.2.
DR   AlphaFoldDB; Q29RL0; -.
DR   SMR; Q29RL0; -.
DR   STRING; 9913.ENSBTAP00000028197; -.
DR   PaxDb; Q29RL0; -.
DR   PRIDE; Q29RL0; -.
DR   Ensembl; ENSBTAT00000028197; ENSBTAP00000028197; ENSBTAG00000021156.
DR   GeneID; 511062; -.
DR   KEGG; bta:511062; -.
DR   CTD; 93594; -.
DR   VEuPathDB; HostDB:ENSBTAG00000021156; -.
DR   VGNC; VGNC:35642; TBC1D31.
DR   eggNOG; KOG0295; Eukaryota.
DR   eggNOG; KOG1093; Eukaryota.
DR   GeneTree; ENSGT00940000153859; -.
DR   HOGENOM; CLU_003330_0_0_1; -.
DR   InParanoid; Q29RL0; -.
DR   OMA; WFEYHPL; -.
DR   OrthoDB; 858041at2759; -.
DR   TreeFam; TF324799; -.
DR   Proteomes; UP000009136; Chromosome 14.
DR   Bgee; ENSBTAG00000021156; Expressed in myometrium and 111 other tissues.
DR   ExpressionAtlas; Q29RL0; baseline and differential.
DR   GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF47923; SSF47923; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..1063
FT                   /note="TBC1 domain family member 31"
FT                   /id="PRO_0000244842"
FT   REPEAT          33..74
FT                   /note="WD 1"
FT   REPEAT          75..116
FT                   /note="WD 2"
FT   REPEAT          117..157
FT                   /note="WD 3"
FT   REPEAT          158..200
FT                   /note="WD 4"
FT   REPEAT          201..248
FT                   /note="WD 5"
FT   REPEAT          249..296
FT                   /note="WD 6"
FT   REPEAT          297..334
FT                   /note="WD 7"
FT   DOMAIN          424..599
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT   COILED          699..951
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1063 AA;  123866 MW;  F3130ED3D147E290 CRC64;
     MQSTDLGSKE SGKIWHRKPS PATRDGIIVN IIHNTSDYLP KVLRFLNVAF DSSGDCLIAG
     DHHGNIYVFD LCGNRFNLVQ RTAQACTALA FNLHRKSEFL VALADYSIKC FDTVTKELVS
     WMRGHESSVF SISVHGSGRY AITTSSDTAQ LWDLDTFQRK RKLNILQSVG IQKVFFLPLS
     NTILSCFKDN SIFAWECDTL VCKYQLPAPP ESSNILYKVF AVTRDGRILA AGGKSNHIHL
     WCLEAKQLFR IIQMPTKVRA IRHLEFLPDS FDAGSNQVLG VLSQDGIMRF INIQTCKLLF
     EIGSLDDGIS SSVISPHGRY IASIMENGSL NIYSVQTLTK EINKPPPPLV KVIEDLPKKK
     GNSGDLKVKV TSGRVRRPAR SRESKIQTRI LKQDLTCGFE KKENELSDGL NKKRLQILLK
     GYGEFPTKYR MFIWRSLLQL PENQTAFSNL IDKGIHVAFL NLQKKYPIKS RKLLRVLQRT
     LSALAHWSAI FSDTPYLPLL AFPFVKLFQN NQLICFEVVA TLIINWCQHW FEYFPNPPIN
     ILSMIENVLA FHDKELLQHF INHDVTSQLY AWPLLETVFS EVLTREEWLK LFDNVFSNHP
     SFLLMTVVAY NICSRAPLLN CKRKDDFEYF FHHRNNLDIS AVIREAYRLL DTTPADIHPD
     SMLDAFVALT KGQYPVFNQY PKFIVDYQTQ ERERIRNDEL DYLRERQAVE EMQAEVDQQR
     VEDEAWYQKQ ELLRRAEETR REILLQEEEK MIQQRQRLAA VRRELKVKEM HLQDAARRRL
     LQLQQDQREM ELRRLDDEIE RKVHMRDREI AATAKDLEMR HLELESQKRL YEKNLSRNQE
     AVAKEMKENA DAYRQKVDVE EHMFHRLIGT DQTQNQKIHK LIEENLAKAE QACLNTDWRI
     QALHKQRCSD LHRNECYQEI AKLLRKNRKK EIEVLNAMME GEAKKWEEAE EKDFHLKSEK
     KTAALSDASR RWFLEKEIHD AQHPCDKVVP KGRDEEFASG CLPRASQLND ISEMESLTQI
     SLNQRKMHWD AMEQDLMERV RNLRQRLVTQ AQNRCQTPHL LAT
 
 
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