TBC31_BOVIN
ID TBC31_BOVIN Reviewed; 1063 AA.
AC Q29RL0;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=TBC1 domain family member 31;
DE AltName: Full=WD repeat-containing protein 67;
GN Name=TBC1D31; Synonyms=WDR67;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hypothalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; BC114127; AAI14128.1; -; mRNA.
DR RefSeq; NP_001039538.1; NM_001046073.2.
DR AlphaFoldDB; Q29RL0; -.
DR SMR; Q29RL0; -.
DR STRING; 9913.ENSBTAP00000028197; -.
DR PaxDb; Q29RL0; -.
DR PRIDE; Q29RL0; -.
DR Ensembl; ENSBTAT00000028197; ENSBTAP00000028197; ENSBTAG00000021156.
DR GeneID; 511062; -.
DR KEGG; bta:511062; -.
DR CTD; 93594; -.
DR VEuPathDB; HostDB:ENSBTAG00000021156; -.
DR VGNC; VGNC:35642; TBC1D31.
DR eggNOG; KOG0295; Eukaryota.
DR eggNOG; KOG1093; Eukaryota.
DR GeneTree; ENSGT00940000153859; -.
DR HOGENOM; CLU_003330_0_0_1; -.
DR InParanoid; Q29RL0; -.
DR OMA; WFEYHPL; -.
DR OrthoDB; 858041at2759; -.
DR TreeFam; TF324799; -.
DR Proteomes; UP000009136; Chromosome 14.
DR Bgee; ENSBTAG00000021156; Expressed in myometrium and 111 other tissues.
DR ExpressionAtlas; Q29RL0; baseline and differential.
DR GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 2.
DR InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF47923; SSF47923; 1.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..1063
FT /note="TBC1 domain family member 31"
FT /id="PRO_0000244842"
FT REPEAT 33..74
FT /note="WD 1"
FT REPEAT 75..116
FT /note="WD 2"
FT REPEAT 117..157
FT /note="WD 3"
FT REPEAT 158..200
FT /note="WD 4"
FT REPEAT 201..248
FT /note="WD 5"
FT REPEAT 249..296
FT /note="WD 6"
FT REPEAT 297..334
FT /note="WD 7"
FT DOMAIN 424..599
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT COILED 699..951
FT /evidence="ECO:0000255"
SQ SEQUENCE 1063 AA; 123866 MW; F3130ED3D147E290 CRC64;
MQSTDLGSKE SGKIWHRKPS PATRDGIIVN IIHNTSDYLP KVLRFLNVAF DSSGDCLIAG
DHHGNIYVFD LCGNRFNLVQ RTAQACTALA FNLHRKSEFL VALADYSIKC FDTVTKELVS
WMRGHESSVF SISVHGSGRY AITTSSDTAQ LWDLDTFQRK RKLNILQSVG IQKVFFLPLS
NTILSCFKDN SIFAWECDTL VCKYQLPAPP ESSNILYKVF AVTRDGRILA AGGKSNHIHL
WCLEAKQLFR IIQMPTKVRA IRHLEFLPDS FDAGSNQVLG VLSQDGIMRF INIQTCKLLF
EIGSLDDGIS SSVISPHGRY IASIMENGSL NIYSVQTLTK EINKPPPPLV KVIEDLPKKK
GNSGDLKVKV TSGRVRRPAR SRESKIQTRI LKQDLTCGFE KKENELSDGL NKKRLQILLK
GYGEFPTKYR MFIWRSLLQL PENQTAFSNL IDKGIHVAFL NLQKKYPIKS RKLLRVLQRT
LSALAHWSAI FSDTPYLPLL AFPFVKLFQN NQLICFEVVA TLIINWCQHW FEYFPNPPIN
ILSMIENVLA FHDKELLQHF INHDVTSQLY AWPLLETVFS EVLTREEWLK LFDNVFSNHP
SFLLMTVVAY NICSRAPLLN CKRKDDFEYF FHHRNNLDIS AVIREAYRLL DTTPADIHPD
SMLDAFVALT KGQYPVFNQY PKFIVDYQTQ ERERIRNDEL DYLRERQAVE EMQAEVDQQR
VEDEAWYQKQ ELLRRAEETR REILLQEEEK MIQQRQRLAA VRRELKVKEM HLQDAARRRL
LQLQQDQREM ELRRLDDEIE RKVHMRDREI AATAKDLEMR HLELESQKRL YEKNLSRNQE
AVAKEMKENA DAYRQKVDVE EHMFHRLIGT DQTQNQKIHK LIEENLAKAE QACLNTDWRI
QALHKQRCSD LHRNECYQEI AKLLRKNRKK EIEVLNAMME GEAKKWEEAE EKDFHLKSEK
KTAALSDASR RWFLEKEIHD AQHPCDKVVP KGRDEEFASG CLPRASQLND ISEMESLTQI
SLNQRKMHWD AMEQDLMERV RNLRQRLVTQ AQNRCQTPHL LAT