ID   TBCC1_XENLA             Reviewed;         547 AA.
AC   Q08AV6;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=TBCC domain-containing protein 1;
GN   Name=tbccd1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the regulation of centrosome and Golgi
CC       apparatus positioning. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBCC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC124991; AAI24992.1; -; mRNA.
DR   RefSeq; NP_001121322.1; NM_001127850.1.
DR   AlphaFoldDB; Q08AV6; -.
DR   SMR; Q08AV6; -.
DR   BioGRID; 932727; 1.
DR   IntAct; Q08AV6; 1.
DR   DNASU; 100158407; -.
DR   GeneID; 100158407; -.
DR   KEGG; xla:100158407; -.
DR   CTD; 100158407; -.
DR   Xenbase; XB-GENE-6252749; tbccd1.L.
DR   OMA; SMHYLRK; -.
DR   OrthoDB; 433967at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 100158407; Expressed in testis and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.160.20.70; -; 1.
DR   InterPro; IPR017901; C-CAP_CF_C-like.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR036223; CAP_C_sf.
DR   InterPro; IPR006599; CARP_motif.
DR   InterPro; IPR039589; TBCC1.
DR   InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR   PANTHER; PTHR16052; PTHR16052; 1.
DR   Pfam; PF07986; TBCC; 1.
DR   SMART; SM00673; CARP; 2.
DR   SUPFAM; SSF69340; SSF69340; 1.
DR   PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..547
FT                   /note="TBCC domain-containing protein 1"
FT                   /id="PRO_0000304949"
FT   DOMAIN          304..435
FT                   /note="C-CAP/cofactor C-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00659"
SQ   SEQUENCE   547 AA;  62653 MW;  5915E28C580BBE25 CRC64;
     MDGSRVQLWA KTDPFLLGAL QMPPPAKFSM HYLRKMASYV RTRATEGCYP RLYWAMWRHI
     ACGKLQIVEE TAWLYFETFL SVFERSVAQS LDWAEVASTC PSSEKYEEIK SQLSVDTLKF
     ILFLYIQQIN KISLRAPMIE SEWPSPRSRS PTPDFVAQSS IYNKVWDDYS HYNFIHNHLT
     YILELLMEPK QLSIVTQSSH CILISAEVVN ALGFLIEGTV DKNRAVNHFL DLAVWQPVQI
     KSGFIETSGA FSFQKLQAWI KECLVINPFG ITACIKSGTK LSWAQQVDGL NKRAKVACNT
     YKVPHTHRMV VMSQISKQTL AKSSKTLVDA RVKIHRCSDC YIYLLSPLRS VTVEKCQNCT
     IILGPVQTVL HIQMCYNVKI IAVCQRLSLL STTNCTFHIL TPTRPLFYCG NQGAVLAPFH
     IRYSMLEDHM AQTGLATVPN SWDRPFLFST ESNNSNIWRL MPPEDFFTFV VPFEMEGDTT
     EIPGGLPPAY SNSVQQRQQK IHTWQKTVKD AGLTREQRKQ FQAVVEMKFN EWLSKTENRH
     QLDSLVS