ID   TBGN_GUITH              Reviewed;         424 AA.
AC   Q9SEA4; Q9SQ06;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 2.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Tubulin gamma chain, nucleomorph;
DE   AltName: Full=Nucleomorph gamma-tubulin;
GN   Name=tubG; Synonyms=gtubNM;
OS   Guillardia theta (Cryptophyte) (Cryptomonas phi).
OG   Nucleomorph.
OC   Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX   NCBI_TaxID=55529;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11323671; DOI=10.1038/35074092;
RA   Douglas S.E., Zauner S., Fraunholz M., Beaton M., Penny S.L., Deng L.-T.,
RA   Wu X., Reith M.E., Cavalier-Smith T., Maier U.-G.;
RT   "The highly reduced genome of an enslaved algal nucleus.";
RL   Nature 410:1091-1096(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-411.
RX   PubMed=10486984; DOI=10.1093/oxfordjournals.molbev.a026221;
RA   Keeling P.J., Deane J.A., Hink-Schauer C., Douglas S.E., Maier U.-G.,
RA   McFadden G.I.;
RT   "The secondary endosymbiont of the cryptomonad Guillardia theta contains
RT   alpha-, beta-, and gamma-tubulin genes.";
RL   Mol. Biol. Evol. 16:1308-1313(1999).
CC   -!- FUNCTION: Tubulin is the major constituent of microtubules. The gamma
CC       chain is found at microtubule organizing centers (MTOC) such as the
CC       spindle poles or the centrosome, suggesting that it is involved in the
CC       minus-end nucleation of microtubule assembly.
CC   -!- SIMILARITY: Belongs to the tubulin family. {ECO:0000305}.
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DR   EMBL; AF165818; AAF24212.4; -; Genomic_DNA.
DR   EMBL; AF119171; AAD55352.1; -; Genomic_DNA.
DR   PIR; B90083; B90083.
DR   RefSeq; XP_001713502.1; XM_001713450.1.
DR   AlphaFoldDB; Q9SEA4; -.
DR   SMR; Q9SEA4; -.
DR   GeneID; 857285; -.
DR   GO; GO:0000930; C:gamma-tubulin complex; IEA:InterPro.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   CDD; cd02188; gamma_tubulin; 1.
DR   Gene3D; 1.10.287.600; -; 1.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   InterPro; IPR002454; Gamma_tubulin.
DR   InterPro; IPR008280; Tub_FtsZ_C.
DR   InterPro; IPR000217; Tubulin.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   InterPro; IPR023123; Tubulin_C.
DR   InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR   PANTHER; PTHR11588; PTHR11588; 1.
DR   Pfam; PF00091; Tubulin; 1.
DR   PRINTS; PR01161; TUBULIN.
DR   SMART; SM00864; Tubulin; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
DR   SUPFAM; SSF55307; SSF55307; 1.
PE   3: Inferred from homology;
KW   GTP-binding; Microtubule; Nucleotide-binding.
FT   CHAIN           1..424
FT                   /note="Tubulin gamma chain, nucleomorph"
FT                   /id="PRO_0000233350"
FT   BINDING         137..143
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   424 AA;  49665 MW;  0685EB51E48FF5F4 CRC64;
     MNNEILTLQV GKTGILTGNE FWKSLVREKN LLSDFSLGKN SPTNDNVFFE ESNESFFIPR
     TIIFDLSERD FNYIMKSNYS KMYDKNRHFI LNKNTGNSWL KGYYEGISNC NLVDNILRKR
     IEKMNSVKYF NVFNSINGGT GAGLSSYLIE YIRNNYPKSF INCCSIFPDL YGNTQVTFQP
     YNSVLSIAWQ GLYCDSNIFF QNHAIENLLT KNQINNELSF RKVNYIIGKT ISIIMNTLNH
     NFTLETLISP LIVNPYLNLF FSTINIDILL SKLRKKRPSM IENKTNQLNE ISMNLDLKSG
     NYLSSIELSN RNFYKLFANS IYDKIFYDQT RFYSQLLNQY DSVIINNNVK KENYSSLTYL
     LNHTSFNPVI KKIIQNFELL KKRNAFLEYY CGEILLDEAN TLFRESKDYI LDIINNYDNI
     LSYY