ID   TBG_CHLRE               Reviewed;         468 AA.
AC   Q39582; O22417;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Tubulin gamma chain;
DE   AltName: Full=Gamma-tubulin;
GN   Name=TUBG; Synonyms=TBG1, TUBC;
OS   Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=3055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=21gr / CC-1690;
RX   PubMed=10223635;
RX   DOI=10.1002/(sici)1097-0169(1999)42:4<285::aid-cm3>3.0.co;2-z;
RA   Silflow C.D., Liu B., LaVoie M., Richardson E.A., Palevitz B.A.;
RT   "Gamma-tubulin in Chlamydomonas: characterization of the gene and
RT   localization of the gene product in cells.";
RL   Cell Motil. Cytoskeleton 42:285-297(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=137c / CC-125;
RA   Trabuco E.C., Dutcher S.K.;
RL   Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Tubulin is the major constituent of microtubules. The gamma
CC       chain is found at microtubule organizing centers (MTOC) such as the
CC       spindle poles, suggesting that it is involved in the minus-end
CC       nucleation of microtubule assembly.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center {ECO:0000250|UniProtKB:P38557}.
CC   -!- SIMILARITY: Belongs to the tubulin family. {ECO:0000305}.
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DR   EMBL; U31545; AAA82610.1; -; Genomic_DNA.
DR   EMBL; AF013109; AAB71841.1; -; Genomic_DNA.
DR   PIR; T07904; T07904.
DR   PIR; T08057; T08057.
DR   RefSeq; XP_001691292.1; XM_001691240.1.
DR   AlphaFoldDB; Q39582; -.
DR   SMR; Q39582; -.
DR   STRING; 3055.EDP05025; -.
DR   EnsemblPlants; PNW82912; PNW82912; CHLRE_06g299300v5.
DR   GeneID; 5716998; -.
DR   Gramene; PNW82912; PNW82912; CHLRE_06g299300v5.
DR   KEGG; cre:CHLRE_06g299300v5; -.
DR   eggNOG; KOG1374; Eukaryota.
DR   HOGENOM; CLU_015718_1_0_1; -.
DR   OMA; EHGINKE; -.
DR   OrthoDB; 687389at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000930; C:gamma-tubulin complex; IEA:InterPro.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   CDD; cd02188; gamma_tubulin; 1.
DR   Gene3D; 1.10.287.600; -; 1.
DR   Gene3D; 3.30.1330.20; -; 1.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   InterPro; IPR002454; Gamma_tubulin.
DR   InterPro; IPR008280; Tub_FtsZ_C.
DR   InterPro; IPR000217; Tubulin.
DR   InterPro; IPR037103; Tubulin/FtsZ-like_C.
DR   InterPro; IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   InterPro; IPR023123; Tubulin_C.
DR   InterPro; IPR017975; Tubulin_CS.
DR   InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR   PANTHER; PTHR11588; PTHR11588; 2.
DR   Pfam; PF00091; Tubulin; 1.
DR   Pfam; PF03953; Tubulin_C; 1.
DR   PRINTS; PR01164; GAMMATUBULIN.
DR   PRINTS; PR01161; TUBULIN.
DR   SMART; SM00864; Tubulin; 1.
DR   SMART; SM00865; Tubulin_C; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
DR   SUPFAM; SSF55307; SSF55307; 1.
DR   PROSITE; PS00227; TUBULIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding.
FT   CHAIN           1..468
FT                   /note="Tubulin gamma chain"
FT                   /id="PRO_0000048451"
FT   BINDING         142..148
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        411
FT                   /note="R -> A (in Ref. 2; AAB71841)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   468 AA;  52158 MW;  DA4BFBC3C03AD1C4 CRC64;
     MPREIINLQV GQCGNQVGSE FWRKLCQEHG IAKDGRLEDF ATLGGDRKDV FFYQADDEQY
     IPRAILLDLE PRVINGIQTS DLRNLFNPEN IFISKEGGGA GNNWASGYTQ GEAVQETLLD
     MIDREAEYCD SLEGFNMCHS IAGGTGSGMG SYMLELISDR YSKKLIQTYS VFPNQSESSD
     VVVQPYNSLL TLKRLTLHAD AVVVLDNTAL DKIAVERLHL HKPDVQQINS LIATVMAAST
     TTLRYPGYMN NDLVGLVASL IPTPRCHFLM TGYTPLTAEN AAGQVTSNIR KTTVLDVMRR
     LLQPKNIMVS THTKSRDIAN AKYISILNII QGEVDPSQVH KSLQRIRERK QANFIEWGPA
     SIQVALSKKS PYVQTAHRVS GLMLANHTSV RHLFNKVLRD YEKLMGPKQE RQAFMQAYRD
     VPRFADAAGG GTALLEEFAD AKEVVQDLAN EYAACESADY IQRQMMAS