ID   TBL13_ARATH             Reviewed;         412 AA.
AC   Q9ZQR5;
DT   19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Protein trichome birefringence-like 13;
GN   Name=TBL13; OrderedLocusNames=At2g14530; ORFNames=T13P21.9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY.
RC   STRAIN=cv. Columbia;
RX   PubMed=17316173; DOI=10.1111/j.1365-313x.2006.02994.x;
RA   Xin Z., Mandaokar A., Chen J., Last R.L., Browse J.;
RT   "Arabidopsis ESK1 encodes a novel regulator of freezing tolerance.";
RL   Plant J. 49:786-799(2007).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=20388664; DOI=10.1104/pp.110.153320;
RA   Bischoff V., Nita S., Neumetzler L., Schindelasch D., Urbain A., Eshed R.,
RA   Persson S., Delmer D., Scheible W.R.;
RT   "TRICHOME BIREFRINGENCE and its homolog AT5G01360 encode plant-specific
RT   DUF231 proteins required for cellulose biosynthesis in Arabidopsis.";
RL   Plant Physiol. 153:590-602(2010).
RN   [6]
RP   3D-STRUCTURE MODELING.
RX   PubMed=20657172; DOI=10.4161/psb.5.8.12414;
RA   Bischoff V., Selbig J., Scheible W.R.;
RT   "Involvement of TBL/DUF231 proteins into cell wall biology.";
RL   Plant Signal. Behav. 5:1057-1059(2010).
CC   -!- FUNCTION: May act as a bridging protein that binds pectin and other
CC       cell wall polysaccharides. Probably involved in maintaining
CC       esterification of pectins (By similarity). May be involved in the
CC       specific O-acetylation of cell wall polymers (By similarity).
CC       {ECO:0000250|UniProtKB:Q9FG35, ECO:0000250|UniProtKB:Q9LY46}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Contains 2 motifs that are conserved in esterases, but
CC       it is unlikely that this protein belongs to the catalytically active
CC       pectin esterases. {ECO:0000305|PubMed:20657172}.
CC   -!- SIMILARITY: Belongs to the PC-esterase family. TBL subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AC006067; AAD15463.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06309.1; -; Genomic_DNA.
DR   EMBL; AY074875; AAL75895.1; -; mRNA.
DR   EMBL; AY124844; AAM70553.1; -; mRNA.
DR   PIR; C84518; C84518.
DR   RefSeq; NP_179059.1; NM_127016.3.
DR   AlphaFoldDB; Q9ZQR5; -.
DR   SMR; Q9ZQR5; -.
DR   STRING; 3702.AT2G14530.1; -.
DR   PaxDb; Q9ZQR5; -.
DR   PRIDE; Q9ZQR5; -.
DR   ProteomicsDB; 234241; -.
DR   EnsemblPlants; AT2G14530.1; AT2G14530.1; AT2G14530.
DR   GeneID; 815940; -.
DR   Gramene; AT2G14530.1; AT2G14530.1; AT2G14530.
DR   KEGG; ath:AT2G14530; -.
DR   Araport; AT2G14530; -.
DR   TAIR; locus:2055200; AT2G14530.
DR   eggNOG; ENOG502QS9I; Eukaryota.
DR   HOGENOM; CLU_020953_1_0_1; -.
DR   InParanoid; Q9ZQR5; -.
DR   OMA; GWNCIAG; -.
DR   OrthoDB; 834476at2759; -.
DR   PhylomeDB; Q9ZQR5; -.
DR   PRO; PR:Q9ZQR5; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9ZQR5; baseline and differential.
DR   Genevisible; Q9ZQR5; AT.
DR   GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016413; F:O-acetyltransferase activity; IBA:GO_Central.
DR   InterPro; IPR026057; PC-Esterase.
DR   InterPro; IPR029962; TBL.
DR   InterPro; IPR029968; TBL13.
DR   InterPro; IPR025846; TBL_N.
DR   PANTHER; PTHR32285; PTHR32285; 1.
DR   PANTHER; PTHR32285:SF12; PTHR32285:SF12; 1.
DR   Pfam; PF13839; PC-Esterase; 1.
DR   Pfam; PF14416; PMR5N; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..412
FT                   /note="Protein trichome birefringence-like 13"
FT                   /id="PRO_0000425379"
FT   TRANSMEM        9..29
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   MOTIF           137..139
FT                   /note="GDS motif"
FT   MOTIF           385..399
FT                   /note="DCXHWCLPGXXDXWN motif"
SQ   SEQUENCE   412 AA;  46462 MW;  1155D765FAD34CCE CRC64;
     MATTSHNKPS LFPLLSLLCF ISIFLLLSLS KRASLSSPKT HRSATVFPPK PDGSLSPLSA
     TCDFSEGSWI YDPNPRSTRY TSSCKEIFKG WNCIRNNKTN GFEISNWRWK PKHCDLPSFD
     PLKFLQSHRN TNIGFVGDSL NRNMFVSLFC MLKSVTGELK KWRPAGADRG FTFSQYNLTI
     AYHRTNLLAR YGRWSANAKG GELESLGFKE GYRVDVDIPD SSWAKASSFH DILILNTGHW
     WWAPSKFDPV KSPMLFFEGG RPILPPIPPA TGLDRVLNNM VNFVEKTKRP GGIIFFRTQS
     PRHFEGGDWD QGGTCQRLQP LLPGKVEEFF SVGNNGTNVE VRLVNQHLYN SLKSRSAFHV
     LDITRMSEYR ADAHPAAAGG KNHDDCMHWC LPGLTDTWND LFVATLHTIK AL