ID   TBL25_ARATH             Reviewed;         456 AA.
AC   Q84JH9; Q9LNI0;
DT   19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Protein trichome birefringence-like 25;
GN   Name=TBL25; OrderedLocusNames=At1g01430; ORFNames=F6F3.23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY.
RC   STRAIN=cv. Columbia;
RX   PubMed=17316173; DOI=10.1111/j.1365-313x.2006.02994.x;
RA   Xin Z., Mandaokar A., Chen J., Last R.L., Browse J.;
RT   "Arabidopsis ESK1 encodes a novel regulator of freezing tolerance.";
RL   Plant J. 49:786-799(2007).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=20388664; DOI=10.1104/pp.110.153320;
RA   Bischoff V., Nita S., Neumetzler L., Schindelasch D., Urbain A., Eshed R.,
RA   Persson S., Delmer D., Scheible W.R.;
RT   "TRICHOME BIREFRINGENCE and its homolog AT5G01360 encode plant-specific
RT   DUF231 proteins required for cellulose biosynthesis in Arabidopsis.";
RL   Plant Physiol. 153:590-602(2010).
RN   [6]
RP   FUNCTION.
RX   PubMed=22086088; DOI=10.1105/tpc.111.091728;
RA   Gille S., de Souza A., Xiong G., Benz M., Cheng K., Schultink A.,
RA   Reca I.B., Pauly M.;
RT   "O-acetylation of Arabidopsis hemicellulose xyloglucan requires AXY4 or
RT   AXY4L, proteins with a TBL and DUF231 domain.";
RL   Plant Cell 23:4041-4053(2011).
RN   [7]
RP   3D-STRUCTURE MODELING.
RX   PubMed=20657172; DOI=10.4161/psb.5.8.12414;
RA   Bischoff V., Selbig J., Scheible W.R.;
RT   "Involvement of TBL/DUF231 proteins into cell wall biology.";
RL   Plant Signal. Behav. 5:1057-1059(2010).
CC   -!- FUNCTION: May be involved in the O-acetylation of mannan
CC       (PubMed:22086088). May act as a bridging protein that binds pectin and
CC       other cell wall polysaccharides. Probably involved in maintaining
CC       esterification of pectins (By similarity).
CC       {ECO:0000250|UniProtKB:Q9FG35, ECO:0000269|PubMed:22086088}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Contains 2 motifs that are conserved in esterases, but
CC       it is unlikely that this protein belongs to the catalytically active
CC       pectin esterases. {ECO:0000305|PubMed:20657172}.
CC   -!- SIMILARITY: Belongs to the PC-esterase family. TBL subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF97338.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC023628; AAF97338.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE27285.1; -; Genomic_DNA.
DR   EMBL; BT004301; AAO42299.1; -; mRNA.
DR   EMBL; BT005623; AAO64043.1; -; mRNA.
DR   PIR; H86144; H86144.
DR   RefSeq; NP_171650.2; NM_100025.3.
DR   AlphaFoldDB; Q84JH9; -.
DR   SMR; Q84JH9; -.
DR   STRING; 3702.AT1G01430.1; -.
DR   PaxDb; Q84JH9; -.
DR   PRIDE; Q84JH9; -.
DR   ProteomicsDB; 234195; -.
DR   EnsemblPlants; AT1G01430.1; AT1G01430.1; AT1G01430.
DR   GeneID; 837247; -.
DR   Gramene; AT1G01430.1; AT1G01430.1; AT1G01430.
DR   KEGG; ath:AT1G01430; -.
DR   Araport; AT1G01430; -.
DR   TAIR; locus:2035342; AT1G01430.
DR   eggNOG; ENOG502QSJI; Eukaryota.
DR   HOGENOM; CLU_020953_6_4_1; -.
DR   InParanoid; Q84JH9; -.
DR   OMA; TNESCHV; -.
DR   OrthoDB; 671011at2759; -.
DR   PhylomeDB; Q84JH9; -.
DR   PRO; PR:Q84JH9; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q84JH9; baseline and differential.
DR   Genevisible; Q84JH9; AT.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016413; F:O-acetyltransferase activity; IDA:TAIR.
DR   InterPro; IPR026057; PC-Esterase.
DR   InterPro; IPR029962; TBL.
DR   InterPro; IPR029985; TBL25/26.
DR   InterPro; IPR025846; TBL_N.
DR   PANTHER; PTHR32285; PTHR32285; 1.
DR   PANTHER; PTHR32285:SF181; PTHR32285:SF181; 1.
DR   Pfam; PF13839; PC-Esterase; 1.
DR   Pfam; PF14416; PMR5N; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..456
FT                   /note="Protein trichome birefringence-like 25"
FT                   /id="PRO_0000425390"
FT   TRANSMEM        26..42
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   MOTIF           172..174
FT                   /note="GDS motif"
FT   MOTIF           426..440
FT                   /note="DCXHWCLPGXXDXWN motif"
SQ   SEQUENCE   456 AA;  52501 MW;  AF46189A60917D1D CRC64;
     MDSLRLISKS IKIEGTPFGS SHQRNQIFLK SVAFFLLIGL AYRFLITNST VSPVPTVRSS
     PESLPPDPSG LTAITQTSAS VDSPANITTI ASQNVSTKCD IFIGNWVPDP SGPIYTNVSC
     RHIQDYQNCL KNGRPDVNYL RWRWQPRDCD LPRFNPEQFL DNMRNKWLAF IGDSISRNHV
     QSLLCILSQV EEVEDIFHDK EYKSRIWRFP SYNFTLSVIW SPFLVKAETF ENGVPFSDIR
     VHLDKLDQKW TDQYINFDYV VISGGKWFLK TTIFHENNTV TGCHYCQGKN NMTELGYLYS
     YRKVLHLVLD FVAEPNHKAQ VLFRTTTPDH FENGEWDSGG FCNRTMPFTE GSEGEMKSED
     VSMRDIELEE FYKTTTTQQE GSNSNIVLLD TTSMSLLRPD GHPGPYRYPN PFAGLKNKEL
     NQVQNDCLHW CLPGPIDSWN DLMVEVMLNR ERQRRE