ID   TBL3_BOVIN              Reviewed;         800 AA.
AC   Q2KJJ5;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Transducin beta-like protein 3;
GN   Name=TBL3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR   EMBL; BC105313; AAI05314.1; -; mRNA.
DR   RefSeq; NP_001040084.2; NM_001046619.2.
DR   AlphaFoldDB; Q2KJJ5; -.
DR   SMR; Q2KJJ5; -.
DR   STRING; 9913.ENSBTAP00000027147; -.
DR   PaxDb; Q2KJJ5; -.
DR   PRIDE; Q2KJJ5; -.
DR   GeneID; 618429; -.
DR   KEGG; bta:618429; -.
DR   CTD; 10607; -.
DR   eggNOG; KOG0319; Eukaryota.
DR   InParanoid; Q2KJJ5; -.
DR   OrthoDB; 1112002at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR   GO; GO:0034511; F:U3 snoRNA binding; IBA:GO_Central.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 4.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR013934; SSU_processome_Utp13.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF08625; Utp13; 1.
DR   Pfam; PF00400; WD40; 9.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 12.
DR   SUPFAM; SSF50978; SSF50978; 2.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 8.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome;
KW   Repeat; Ubl conjugation; WD repeat.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q12788"
FT   CHAIN           2..800
FT                   /note="Transducin beta-like protein 3"
FT                   /id="PRO_0000362979"
FT   REPEAT          64..105
FT                   /note="WD 1"
FT   REPEAT          107..146
FT                   /note="WD 2"
FT   REPEAT          149..190
FT                   /note="WD 3"
FT   REPEAT          193..232
FT                   /note="WD 4"
FT   REPEAT          245..284
FT                   /note="WD 5"
FT   REPEAT          290..329
FT                   /note="WD 6"
FT   REPEAT          332..372
FT                   /note="WD 7"
FT   REPEAT          374..413
FT                   /note="WD 8"
FT   REPEAT          419..459
FT                   /note="WD 9"
FT   REPEAT          477..516
FT                   /note="WD 10"
FT   REPEAT          519..560
FT                   /note="WD 11"
FT   REPEAT          562..602
FT                   /note="WD 12"
FT   REPEAT          604..642
FT                   /note="WD 13"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12788"
FT   MOD_RES         257
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q12788"
FT   CROSSLNK        407
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q12788"
SQ   SEQUENCE   800 AA;  88084 MW;  A51FBEF4612AA7B2 CRC64;
     MAEVAAGVGR FKSNYAVERK IEPFYKGGKV QLDQTGQHLF CVCGTRVNIL DVASGAVLRS
     LEQEDQEDIT AFDLSPDDKV LVTASRALLL AQWAWQEGSV TRLWKAIHTA PVATMAFDPT
     STLLATGGCD GAVRVWDVVR CYGTHHFRGS PGVVHLVAFH PDPARLLLFS SAADTSIRVW
     SLQERSCLAV LTAHYSAVTS LTFSADGHTM LSSGRDKICV IWDLRSLQAT RTVPVFESVE
     AAVLLPEEPA PELGVKSAGL HFLTAGDQGA LRVWEAASGR CVHAQQRLRG PGRELTHCTL
     AHAAGLLLSV TADHNLLLYD ARSLRLRKQF AGYSEEVLDV RFLGPEDSHV VVASNSPCLK
     VFDLQTSACQ ILHGHTDIVL ALDVFRKGRL FASCAKDQSI RVWRMNKSGE VACVAQGSGH
     THSVGTICCS RLKETFLVTG SQDCTVKLWP LPEALLSKGT GHEGGPVFLQ AQATQHCHDK
     DINSVAVAPN DKLLATGSQD RTAKLWALPR CQLLGTFSGH RRGLWCVQFS PMDQVLATAS
     ADGTIKLWAL QDFSCLKTFE GHDASVLKVA FVSRGTQLLS SGSDGLLKLW TIKNNECVRT
     LDAHEDKVWG LHCSRLDDRA LTGASDSRVV LWKDVTEAEQ AEEQAKREEQ VVKQQELDNL
     LHEKRYLRAL GLAISLDRPH TVLTVIQAIR RDPESCEKLE TTVLQLRRDQ KEALLRFCVT
     WNTNSRHCHE AQAVLGVLLR HEAPDELLTY DGVRASLEGL LPYTERHFQR LSRMLQAATF
     LDFLWHNMKL PALPTAPAAL