TBL42_ARATH
ID TBL42_ARATH Reviewed; 359 AA.
AC Q9ZV89; F4IBU0;
DT 19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Protein trichome birefringence-like 42;
GN Name=TBL42; OrderedLocusNames=At1g78710; ORFNames=F9K20.25;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RC STRAIN=cv. Columbia;
RX PubMed=17316173; DOI=10.1111/j.1365-313x.2006.02994.x;
RA Xin Z., Mandaokar A., Chen J., Last R.L., Browse J.;
RT "Arabidopsis ESK1 encodes a novel regulator of freezing tolerance.";
RL Plant J. 49:786-799(2007).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=20388664; DOI=10.1104/pp.110.153320;
RA Bischoff V., Nita S., Neumetzler L., Schindelasch D., Urbain A., Eshed R.,
RA Persson S., Delmer D., Scheible W.R.;
RT "TRICHOME BIREFRINGENCE and its homolog AT5G01360 encode plant-specific
RT DUF231 proteins required for cellulose biosynthesis in Arabidopsis.";
RL Plant Physiol. 153:590-602(2010).
RN [5]
RP 3D-STRUCTURE MODELING.
RX PubMed=20657172; DOI=10.4161/psb.5.8.12414;
RA Bischoff V., Selbig J., Scheible W.R.;
RT "Involvement of TBL/DUF231 proteins into cell wall biology.";
RL Plant Signal. Behav. 5:1057-1059(2010).
CC -!- FUNCTION: May act as a bridging protein that binds pectin and other
CC cell wall polysaccharides. Probably involved in maintaining
CC esterification of pectins (By similarity). May be involved in the
CC specific O-acetylation of cell wall polymers (By similarity).
CC {ECO:0000250|UniProtKB:Q9FG35, ECO:0000250|UniProtKB:Q9LY46}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC membrane protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9ZV89-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9ZV89-2; Sequence=VSP_053697, VSP_053698;
CC -!- MISCELLANEOUS: Contains 2 motifs that are conserved in esterases, but
CC it is unlikely that this protein belongs to the catalytically active
CC pectin esterases. {ECO:0000305|PubMed:20657172}.
CC -!- SIMILARITY: Belongs to the PC-esterase family. TBL subfamily.
CC {ECO:0000305}.
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DR EMBL; AC005679; AAC83039.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36141.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36142.1; -; Genomic_DNA.
DR PIR; A96816; A96816.
DR RefSeq; NP_001154476.1; NM_001161004.1. [Q9ZV89-2]
DR RefSeq; NP_177992.1; NM_106518.2. [Q9ZV89-1]
DR AlphaFoldDB; Q9ZV89; -.
DR SMR; Q9ZV89; -.
DR PaxDb; Q9ZV89; -.
DR PRIDE; Q9ZV89; -.
DR ProteomicsDB; 234204; -. [Q9ZV89-1]
DR EnsemblPlants; AT1G78710.1; AT1G78710.1; AT1G78710. [Q9ZV89-1]
DR EnsemblPlants; AT1G78710.2; AT1G78710.2; AT1G78710. [Q9ZV89-2]
DR GeneID; 844207; -.
DR Gramene; AT1G78710.1; AT1G78710.1; AT1G78710. [Q9ZV89-1]
DR Gramene; AT1G78710.2; AT1G78710.2; AT1G78710. [Q9ZV89-2]
DR KEGG; ath:AT1G78710; -.
DR Araport; AT1G78710; -.
DR TAIR; locus:2037498; AT1G78710.
DR eggNOG; ENOG502QS9I; Eukaryota.
DR HOGENOM; CLU_020953_3_0_1; -.
DR InParanoid; Q9ZV89; -.
DR OMA; HTNEGED; -.
DR OrthoDB; 730596at2759; -.
DR PhylomeDB; Q9ZV89; -.
DR PRO; PR:Q9ZV89; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZV89; baseline and differential.
DR Genevisible; Q9ZV89; AT.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016413; F:O-acetyltransferase activity; IBA:GO_Central.
DR InterPro; IPR026057; PC-Esterase.
DR InterPro; IPR029962; TBL.
DR InterPro; IPR025846; TBL_N.
DR PANTHER; PTHR32285; PTHR32285; 1.
DR Pfam; PF13839; PC-Esterase; 1.
DR Pfam; PF14416; PMR5N; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Membrane; Reference proteome; Signal-anchor;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..359
FT /note="Protein trichome birefringence-like 42"
FT /id="PRO_0000425407"
FT TRANSMEM 7..25
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT MOTIF 110..112
FT /note="GDS motif"
FT MOTIF 335..349
FT /note="DCXHWCLPGXXDXWN motif"
FT VAR_SEQ 1..19
FT /note="MNFHQVLFLLLLIFLVDLS -> MILNSLLETQAP (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_053697"
FT VAR_SEQ 209..261
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_053698"
SQ SEQUENCE 359 AA; 40568 MW; A9887DD29786278B CRC64;
MNFHQVLFLL LLIFLVDLSD YGVLADKTND GYKNATKCNI YQGRWIYDNS SNPLYGTSTC
PFIGLDCQKF GRPDKNYLHY RWQPTGCDIP RFNGRDFLTR FKGKKILFVG DSLSNNMWVS
LSCMLHAAVP NAKYTFQLNK GLSTFTIPEY GISVNFLKNG FLVDLVSDKT RGLILKLDSI
SRGNQWLGSD VAIFNTFHWW SHTGRAKTWD YFQTGDKIVK EMNRMEAFKI ALTTWSKWID
HNIDPSKTRV FYQGVSPVHL NGGEWGKPGK TCLGETVPVQ GPSYPGRPNE GEAIVKSVIG
RMAKPVELLD VTAMTEMRKD GHPSIYAGGG DRLNDCSHWC LPGVPDAWNQ LLYTALLSH
