ID   TBL7_ARATH              Reviewed;         445 AA.
AC   F4I037; Q9FVP8;
DT   19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Protein trichome berefringence-like 7;
GN   Name=TBL7; OrderedLocusNames=At1g48880; ORFNames=F27K7.9;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RC   STRAIN=cv. Columbia;
RX   PubMed=17316173; DOI=10.1111/j.1365-313x.2006.02994.x;
RA   Xin Z., Mandaokar A., Chen J., Last R.L., Browse J.;
RT   "Arabidopsis ESK1 encodes a novel regulator of freezing tolerance.";
RL   Plant J. 49:786-799(2007).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=20388664; DOI=10.1104/pp.110.153320;
RA   Bischoff V., Nita S., Neumetzler L., Schindelasch D., Urbain A., Eshed R.,
RA   Persson S., Delmer D., Scheible W.R.;
RT   "TRICHOME BIREFRINGENCE and its homolog AT5G01360 encode plant-specific
RT   DUF231 proteins required for cellulose biosynthesis in Arabidopsis.";
RL   Plant Physiol. 153:590-602(2010).
RN   [5]
RP   3D-STRUCTURE MODELING.
RX   PubMed=20657172; DOI=10.4161/psb.5.8.12414;
RA   Bischoff V., Selbig J., Scheible W.R.;
RT   "Involvement of TBL/DUF231 proteins into cell wall biology.";
RL   Plant Signal. Behav. 5:1057-1059(2010).
CC   -!- FUNCTION: May act as a bridging protein that binds pectin and other
CC       cell wall polysaccharides. Probably involved in maintaining
CC       esterification of pectins (By similarity). May be involved in the
CC       specific O-acetylation of cell wall polymers (By similarity).
CC       {ECO:0000250|UniProtKB:Q9FG35, ECO:0000250|UniProtKB:Q9LY46}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC       membrane protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Contains 2 motifs that are conserved in esterases, but
CC       it is unlikely that this protein belongs to the catalytically active
CC       pectin esterases. {ECO:0000305|PubMed:20657172}.
CC   -!- SIMILARITY: Belongs to the PC-esterase family. TBL subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG29735.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC084414; AAG29735.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE32362.1; -; Genomic_DNA.
DR   PIR; F96526; F96526.
DR   RefSeq; NP_175319.2; NM_103782.3.
DR   AlphaFoldDB; F4I037; -.
DR   SMR; F4I037; -.
DR   STRING; 3702.AT1G48880.1; -.
DR   iPTMnet; F4I037; -.
DR   PaxDb; F4I037; -.
DR   PRIDE; F4I037; -.
DR   ProteomicsDB; 233013; -.
DR   EnsemblPlants; AT1G48880.1; AT1G48880.1; AT1G48880.
DR   GeneID; 841310; -.
DR   Gramene; AT1G48880.1; AT1G48880.1; AT1G48880.
DR   KEGG; ath:AT1G48880; -.
DR   Araport; AT1G48880; -.
DR   TAIR; locus:2028533; AT1G48880.
DR   eggNOG; ENOG502QSWQ; Eukaryota.
DR   HOGENOM; CLU_020953_0_1_1; -.
DR   InParanoid; F4I037; -.
DR   OMA; HEWSSAD; -.
DR   OrthoDB; 773400at2759; -.
DR   PRO; PR:F4I037; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; F4I037; baseline and differential.
DR   Genevisible; F4I037; AT.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016413; F:O-acetyltransferase activity; IBA:GO_Central.
DR   InterPro; IPR026057; PC-Esterase.
DR   InterPro; IPR029962; TBL.
DR   InterPro; IPR029964; TBL7.
DR   InterPro; IPR025846; TBL_N.
DR   PANTHER; PTHR32285; PTHR32285; 1.
DR   PANTHER; PTHR32285:SF34; PTHR32285:SF34; 1.
DR   Pfam; PF13839; PC-Esterase; 1.
DR   Pfam; PF14416; PMR5N; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal-anchor; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..445
FT                   /note="Protein trichome berefringence-like 7"
FT                   /id="PRO_0000425373"
FT   TRANSMEM        69..89
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   MOTIF           188..190
FT                   /note="GDS motif"
FT   MOTIF           418..432
FT                   /note="DCXHWCLPGXXDXWN motif"
SQ   SEQUENCE   445 AA;  50617 MW;  3215F97455BB976D CRC64;
     MSNFTKSSSF NRRALSSLAI ESPRNSSSSV FTSPIGSAFA SPRSQNFGGS PRPSTNRLKE
     ISYLFQVLII AGTIVSFLVI IAGGYLYVVP SLGQTFLGYN GALEFNSSVV GDTECDIFDG
     NWVVDDNYPL YNASECPFVE KGFNCLGNGR GHDEYLKWRW KPKHCTVPRF EVRDVLKRLR
     GKRIVFVGDS MSRTQWESLI CMLMTGLEDK RSVYEVNGNN ITKRIRFLGV RFSSYNFTVE
     FYRSVFLVQP GRLRWHAPKR VKSTLKLDVL DVINHEWSSA DFLIFNTGQW WVPGKLFETG
     CYFQVGNSLR LGMSIPAAYR VALETWASWI ESTVDPNKTR VLFRTFEPSH WSDHRSCNVT
     KYPAPDTEGR DKSIFSEMIK EVVKNMTIPV SILDVTSMSA FRSDGHVGLW SDNPLVPDCS
     HWCLPGVPDI WNEILLFFLF RQPVQ