TBP1_MAIZE
ID TBP1_MAIZE Reviewed; 200 AA.
AC P50158; Q43865;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=TATA-box-binding protein 1;
DE AltName: Full=TATA sequence-binding protein 1;
DE Short=TBP-1;
DE AltName: Full=TATA-binding factor 1;
DE AltName: Full=TATA-box factor 1;
DE AltName: Full=Transcription initiation factor TFIID TBP-1 subunit;
GN Name=TBP1;
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1577169; DOI=10.1016/0014-5793(92)80260-n;
RA Haass M.M., Feix G.;
RT "Two different cDNAs encoding TFIID proteins of maize.";
RL FEBS Lett. 301:294-298(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. B73 Inbred; TISSUE=Leaf blade, and Sheath;
RX PubMed=8312743; DOI=10.2307/3869744;
RA Vogel J.M., Roth B., Cigan M., Freeling M.;
RT "Expression of the two maize TATA binding protein genes and function of the
RT encoded TBP proteins by complementation in yeast.";
RL Plant Cell 5:1627-1638(1993).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. RTCS 2; TISSUE=Endosperm;
RX PubMed=8863736; DOI=10.1016/0378-1119(96)00437-4;
RA Goddemeier M.L., Feix G.;
RT "Genomic structure of the maize TATA-box binding protein 1 (TBP-1):
RT conserved exon/intron structure in eukaryotic TBP genes.";
RL Gene 174:111-114(1996).
CC -!- FUNCTION: General transcription factor that functions at the core of
CC the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA
CC box is the initial transcriptional step of the pre-initiation complex
CC (PIC), playing a role in the activation of eukaryotic genes transcribed
CC by RNA polymerase II.
CC -!- SUBUNIT: Belongs to the TFIID complex together with the TBP-associated
CC factors (TAFs). Binds DNA as monomer.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA62224.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; L13301; AAA65941.1; -; mRNA.
DR EMBL; X90652; CAA62224.1; ALT_SEQ; Genomic_DNA.
DR PIR; S21140; S21140.
DR PIR; T03386; T03386.
DR RefSeq; NP_001105318.1; NM_001111848.2.
DR AlphaFoldDB; P50158; -.
DR SMR; P50158; -.
DR PaxDb; P50158; -.
DR EnsemblPlants; Zm00001eb052680_T001; Zm00001eb052680_P001; Zm00001eb052680.
DR GeneID; 542240; -.
DR Gramene; Zm00001eb052680_T001; Zm00001eb052680_P001; Zm00001eb052680.
DR KEGG; zma:542240; -.
DR MaizeGDB; 25978; -.
DR eggNOG; KOG3302; Eukaryota.
DR HOGENOM; CLU_060161_4_2_1; -.
DR OMA; QNPDEAE; -.
DR OrthoDB; 1219067at2759; -.
DR Proteomes; UP000007305; Chromosome 1.
DR ExpressionAtlas; P50158; baseline and differential.
DR Genevisible; P50158; ZM.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR CDD; cd04516; TBP_eukaryotes; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR InterPro; IPR033710; TBP_eukaryotic.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription.
FT CHAIN 1..200
FT /note="TATA-box-binding protein 1"
FT /id="PRO_0000153978"
FT REPEAT 25..101
FT /note="1"
FT REPEAT 115..192
FT /note="2"
FT VARIANT 5
FT /note="G -> R (in strain: cv. RTCS 2)"
SQ SEQUENCE 200 AA; 22323 MW; 75B9E6D511024A41 CRC64;
MAEPGLEDSQ PVDLSKHPSG IVPTLQNIVS TVNLDCKLDL KAIALQARNA EYNPKRFAAV
IMRIREPKTT ALIFASGKMV CTGAKSEQQS KLAARKYARI IQKLGFPAKF KDFKIQNIVG
SCDVKFPIRL EGLAYSHGAF SSYEPELFPG LIYRMKQPKI VLLIFVSGKI VLTGAKVREE
TYTAFENIYP VLAEFRKVQQ
