ID   TBP1_METAC              Reviewed;         183 AA.
AC   Q8TI26;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=TATA-box-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=Box A-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=BAP 1 {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA sequence-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=TBP 1 {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA-box factor 1 {ECO:0000255|HAMAP-Rule:MF_00408};
GN   Name=tbp1 {ECO:0000255|HAMAP-Rule:MF_00408}; Synonyms=tbp-1;
GN   OrderedLocusNames=MA_4331;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00408}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE010299; AAM07674.1; -; Genomic_DNA.
DR   RefSeq; WP_011024211.1; NC_003552.1.
DR   AlphaFoldDB; Q8TI26; -.
DR   SMR; Q8TI26; -.
DR   STRING; 188937.MA_4331; -.
DR   EnsemblBacteria; AAM07674; AAM07674; MA_4331.
DR   GeneID; 41607741; -.
DR   KEGG; mac:MA_4331; -.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   InParanoid; Q8TI26; -.
DR   OMA; NCEYEPE; -.
DR   OrthoDB; 83880at2157; -.
DR   PhylomeDB; Q8TI26; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..183
FT                   /note="TATA-box-binding protein 1"
FT                   /id="PRO_0000154005"
FT   REPEAT          8..84
FT                   /note="1"
FT   REPEAT          99..177
FT                   /note="2"
SQ   SEQUENCE   183 AA;  19884 MW;  D9DB838CCDAD5B26 CRC64;
     MSESSIKIEN VVASTKLAEE FDLTVIESEF EGAEYNKQKF PGLVYRVSDP KAAFLVFTSG
     KVVCTGAKNV ADVHTVIGNM AKKLNSIGIK TMENPQITVQ NIVASADLHT ILNLNAIAIG
     LGLENIEYEP EQFPGLVYRI DEPKVVVLIF SSGKLVVTGG KSPEDCERGV EVVRQQLDNM
     GLL