TBP1_WHEAT
ID TBP1_WHEAT Reviewed; 233 AA.
AC P26356;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=TATA-box-binding protein 1;
DE AltName: Full=TATA sequence-binding protein 1;
DE Short=TBP-1;
DE AltName: Full=TATA-binding factor 1;
DE AltName: Full=TATA-box factor 1;
DE AltName: Full=Transcription initiation factor TFIID TBP-1 subunit;
GN Name=TBP1; Synonyms=TFIID;
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1643287; DOI=10.1007/bf00027083;
RA Kawata T., Minami M., Tamura T., Sumita K., Iwabuchi M.;
RT "Isolation and characterization of a cDNA clone encoding the TATA box-
RT binding protein (TFIID) from wheat.";
RL Plant Mol. Biol. 19:867-872(1992).
CC -!- FUNCTION: General transcription factor that functions at the core of
CC the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA
CC box is the initial transcriptional step of the pre-initiation complex
CC (PIC), playing a role in the activation of eukaryotic genes transcribed
CC by RNA polymerase II.
CC -!- SUBUNIT: Belongs to the TFIID complex together with the TBP-associated
CC factors (TAFs). Binds DNA as monomer.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; X59874; CAA42531.1; -; mRNA.
DR PIR; S23522; S23522.
DR AlphaFoldDB; P26356; -.
DR SMR; P26356; -.
DR STRING; 4565.Traes_1AL_60B57FD46.2; -.
DR PRIDE; P26356; -.
DR EnsemblPlants; TraesCAD_scaffold_103774_01G000100.1; TraesCAD_scaffold_103774_01G000100.1; TraesCAD_scaffold_103774_01G000100.
DR EnsemblPlants; TraesCLE_scaffold_121292_01G000100.1; TraesCLE_scaffold_121292_01G000100.1; TraesCLE_scaffold_121292_01G000100.
DR EnsemblPlants; TraesCS1A02G139600.1; TraesCS1A02G139600.1; TraesCS1A02G139600.
DR EnsemblPlants; TraesPAR_scaffold_122403_01G000100.1; TraesPAR_scaffold_122403_01G000100.1; TraesPAR_scaffold_122403_01G000100.
DR EnsemblPlants; TraesROB_scaffold_101976_01G000100.1; TraesROB_scaffold_101976_01G000100.1; TraesROB_scaffold_101976_01G000100.
DR EnsemblPlants; TraesWEE_scaffold_135801_01G000100.1; TraesWEE_scaffold_135801_01G000100.1; TraesWEE_scaffold_135801_01G000100.
DR Gramene; TraesCAD_scaffold_103774_01G000100.1; TraesCAD_scaffold_103774_01G000100.1; TraesCAD_scaffold_103774_01G000100.
DR Gramene; TraesCLE_scaffold_121292_01G000100.1; TraesCLE_scaffold_121292_01G000100.1; TraesCLE_scaffold_121292_01G000100.
DR Gramene; TraesCS1A02G139600.1; TraesCS1A02G139600.1; TraesCS1A02G139600.
DR Gramene; TraesPAR_scaffold_122403_01G000100.1; TraesPAR_scaffold_122403_01G000100.1; TraesPAR_scaffold_122403_01G000100.
DR Gramene; TraesROB_scaffold_101976_01G000100.1; TraesROB_scaffold_101976_01G000100.1; TraesROB_scaffold_101976_01G000100.
DR Gramene; TraesWEE_scaffold_135801_01G000100.1; TraesWEE_scaffold_135801_01G000100.1; TraesWEE_scaffold_135801_01G000100.
DR eggNOG; KOG3302; Eukaryota.
DR OMA; CCTYEPE; -.
DR Proteomes; UP000019116; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR CDD; cd04516; TBP_eukaryotes; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR InterPro; IPR033710; TBP_eukaryotic.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription.
FT CHAIN 1..233
FT /note="TATA-box-binding protein 1"
FT /id="PRO_0000153985"
FT REPEAT 58..134
FT /note="1"
FT REPEAT 148..225
FT /note="2"
SQ SEQUENCE 233 AA; 24944 MW; 0DACBA803A60B3D1 CRC64;
MAAAAVDPMV LGLGTSGGAS GSGVVGGGVG RAGGGGAVME GAQPVDLARH PSGIVPVLQN
IVSTVNLDCR LDLKQIALQA RNAEYNPKRF AAVIMRIRDP KTTALIFASG KMVCTGAKSE
EHSKLAARKY ARIVQKLGFP ATFKDFKIQN IVASCDVKFP IRLEGLAYSH GAFSSYEPEL
FPGLIYRMKQ PKIVLLVFVS GKIVLTGAKV RDEIYAAFEN IYPVLTEYRK SQQ
