TBP2_METMA
ID TBP2_METMA Reviewed; 183 AA.
AC Q8PY36;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 120.
DE RecName: Full=TATA-box-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=Box A-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=BAP 2 {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA sequence-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=TBP 2 {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA-box factor 2 {ECO:0000255|HAMAP-Rule:MF_00408};
GN Name=tbp2 {ECO:0000255|HAMAP-Rule:MF_00408}; OrderedLocusNames=MM_1028;
OS Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS 11833 / OCM 88) (Methanosarcina frisia).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=192952;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RX PubMed=12125824;
RA Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C.,
RA Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S.,
RA Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P.,
RA Fritz H.-J., Gottschalk G.;
RT "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT between Bacteria and Archaea.";
RL J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC Rule:MF_00408}.
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DR EMBL; AE008384; AAM30724.1; -; Genomic_DNA.
DR RefSeq; WP_011032977.1; NC_003901.1.
DR AlphaFoldDB; Q8PY36; -.
DR SMR; Q8PY36; -.
DR IntAct; Q8PY36; 1.
DR MINT; Q8PY36; -.
DR STRING; 192952.MM_1028; -.
DR EnsemblBacteria; AAM30724; AAM30724; MM_1028.
DR GeneID; 44085725; -.
DR GeneID; 66137552; -.
DR KEGG; mma:MM_1028; -.
DR PATRIC; fig|192952.21.peg.1204; -.
DR eggNOG; arCOG01764; Archaea.
DR HOGENOM; CLU_060161_4_3_2; -.
DR OMA; NCEYEPE; -.
DR Proteomes; UP000000595; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..183
FT /note="TATA-box-binding protein 2"
FT /id="PRO_0000154011"
FT REPEAT 8..84
FT /note="1"
FT REPEAT 99..177
FT /note="2"
SQ SEQUENCE 183 AA; 19828 MW; AEB64B104D290F77 CRC64;
MSESSIKIEN VVASTKLAEE FDLTVIESQF EGAEYNKQKF PGLVYRVSDP KAAFLVFTSG
KVVCTGAKNV ADVHTVIGNM AKKLNSIGIK TMENPQITVQ NIVASADLHT ILNLNAIAIG
LGLENIEYEP EQFPGLVYRI DEPKVVVLIF SSGKLVVTGG KTPEDCESGV EVVRQQLDNM
GLL
