TBP2_WHEAT
ID TBP2_WHEAT Reviewed; 201 AA.
AC Q02879;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=TATA-box-binding protein 2;
DE AltName: Full=TATA sequence-binding protein 2;
DE Short=TBP-2;
DE AltName: Full=TATA-binding factor 2;
DE AltName: Full=TATA-box factor 2;
DE AltName: Full=Transcription initiation factor TFIID TBP-2 subunit;
GN Name=TBP2; Synonyms=TFIID;
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8464747; DOI=10.1093/nar/21.6.1494;
RA Apsit V., Freeberg J.A., Chase M.R., Davis E.A., Ackerman S.J.;
RT "Wheat TFIID TATA binding protein.";
RL Nucleic Acids Res. 21:1494-1494(1993).
CC -!- FUNCTION: General transcription factor that functions at the core of
CC the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA
CC box is the initial transcriptional step of the pre-initiation complex
CC (PIC), playing a role in the activation of eukaryotic genes transcribed
CC by RNA polymerase II.
CC -!- SUBUNIT: Belongs to the TFIID complex together with the TBP-associated
CC factors (TAFs). Binds DNA as monomer.
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; Z18804; CAA79268.1; -; mRNA.
DR EMBL; L07604; AAA34307.1; -; mRNA.
DR PIR; S30216; S30216.
DR AlphaFoldDB; Q02879; -.
DR SMR; Q02879; -.
DR STRING; 4565.Traes_4BS_4F52653D8.1; -.
DR eggNOG; KOG3302; Eukaryota.
DR Proteomes; UP000019116; Unplaced.
DR ExpressionAtlas; Q02879; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR CDD; cd04516; TBP_eukaryotes; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR InterPro; IPR033710; TBP_eukaryotic.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription.
FT CHAIN 1..201
FT /note="TATA-box-binding protein 2"
FT /id="PRO_0000153986"
FT REPEAT 26..102
FT /note="1"
FT REPEAT 116..193
FT /note="2"
SQ SEQUENCE 201 AA; 22411 MW; 4C0941CB3A04BF9D CRC64;
MAEAAALEGS EPVDLTKHPS GIIPTLQNIV STVNLDCKLD LKAIALQARN AEYNPKRFAA
VIMRIREPKT TALIFASGKM VCTGAKSEQQ SKLAARKYAR IIQKLGFPAK FKDFKIQNIV
ASCDVKFPIR LEGLAYSHGA FSSYEPELFP GLIYRMRQPK IVLLIFVSGK IVLTGAKVRE
ETYSAFENIY PVLTEFRKVQ Q