TBP3_METAC
ID TBP3_METAC Reviewed; 185 AA.
AC Q8TTZ7;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=TATA-box-binding protein 3 {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=Box A-binding protein 3 {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=BAP 3 {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA sequence-binding protein 3 {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=TBP 3 {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA-box factor 3 {ECO:0000255|HAMAP-Rule:MF_00408};
GN Name=tbp3 {ECO:0000255|HAMAP-Rule:MF_00408}; Synonyms=tbp-3;
GN OrderedLocusNames=MA_0278;
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC Rule:MF_00408}.
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DR EMBL; AE010299; AAM03731.1; -; Genomic_DNA.
DR RefSeq; WP_011020336.1; NC_003552.1.
DR AlphaFoldDB; Q8TTZ7; -.
DR SMR; Q8TTZ7; -.
DR STRING; 188937.MA_0278; -.
DR EnsemblBacteria; AAM03731; AAM03731; MA_0278.
DR GeneID; 1472170; -.
DR KEGG; mac:MA_0278; -.
DR HOGENOM; CLU_060161_4_3_2; -.
DR InParanoid; Q8TTZ7; -.
DR OMA; FHFKIAD; -.
DR OrthoDB; 83880at2157; -.
DR PhylomeDB; Q8TTZ7; -.
DR Proteomes; UP000002487; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..185
FT /note="TATA-box-binding protein 3"
FT /id="PRO_0000154007"
FT REPEAT 7..84
FT /note="1"
FT REPEAT 100..178
FT /note="2"
SQ SEQUENCE 185 AA; 20048 MW; 4406C7A48E04FED4 CRC64;
MESTITIENV VASTALATEF DLVKIMDSGL EGAEYNKTKF PGLVYRIDNP KAAFLIFTSG
KVVCTGAKTI NNAHKAITNL ANKLKDIGCD KINLEPEIHV QNIVASADLK TTLNLNTIAI
AFGLENVEYE PEVFPGLIYR VEAPKVVVLV FSSGKLVITG GKCEEDCNGG LRIVRKEFDN
LGLLC
