TBPB_HALSA
ID TBPB_HALSA Reviewed; 186 AA.
AC Q48325;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=TATA-box-binding protein B;
DE AltName: Full=Box A-binding protein B;
DE Short=BAP B;
DE AltName: Full=TATA sequence-binding protein B;
DE Short=TBP B;
DE AltName: Full=TATA-box factor B;
GN Name=tbpB1; OrderedLocusNames=VNG_5052G;
GN and
GN Name=tbpB2; OrderedLocusNames=VNG_5245G;
GN and
GN Name=tbpB3; OrderedLocusNames=VNG_6050G;
GN and
GN Name=tbpB4; OrderedLocusNames=VNG_6476G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OG Plasmid pNRC100, and Plasmid pNRC200.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9363785; DOI=10.1111/j.1432-1033.1997.t01-1-00318.x;
RA Soppa J., Link T.A.;
RT "The TATA-box-binding protein (TBP) of Halobacterium salinarum. Cloning of
RT the tbp gene, heterologous production of TBP and folding of TBP into a
RT native conformation.";
RL Eur. J. Biochem. 249:318-324(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1; PLASMID=pNRC100;
RX PubMed=9847077; DOI=10.1101/gr.8.11.1131;
RA Ng W.V., Ciufo S.A., Smith T.M., Bumgarner R.E., Baskin D., Faust J.,
RA Hall B., Loretz C., Seto J., Slagel J., Hood L., DasSarma S.;
RT "Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid
RT or minichromosome?";
RL Genome Res. 8:1131-1141(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1; PLASMID=pNRC200;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; X93206; CAA63691.1; -; Genomic_DNA.
DR EMBL; AF016485; AAC82955.1; -; Genomic_DNA.
DR EMBL; AF016485; AAC82822.1; -; Genomic_DNA.
DR EMBL; AE004438; AAG21065.1; -; Genomic_DNA.
DR EMBL; AE004438; AAG20743.1; -; Genomic_DNA.
DR PIR; T08255; T08255.
DR PIR; T44922; T44922.
DR RefSeq; WP_010890411.1; NZ_BK010831.1.
DR AlphaFoldDB; Q48325; -.
DR SMR; Q48325; -.
DR EnsemblBacteria; AAC82822; AAC82822; AAC82822.
DR EnsemblBacteria; AAC82955; AAC82955; AAC82955.
DR EnsemblBacteria; AAG20743; AAG20743; VNG_6050G.
DR EnsemblBacteria; AAG21065; AAG21065; VNG_6476G.
DR GeneID; 1449440; -.
DR KEGG; hal:AAC82955.1; -.
DR KEGG; hal:tbpB; -.
DR KEGG; hal:VNG_6050G; -.
DR KEGG; hal:VNG_6476G; -.
DR PATRIC; fig|64091.14.peg.2115; -.
DR HOGENOM; CLU_060161_4_3_2; -.
DR InParanoid; Q48325; -.
DR OMA; QNPDEAE; -.
DR OrthoDB; 83880at2157; -.
DR Proteomes; UP000000554; Plasmid pNRC100.
DR Proteomes; UP000000554; Plasmid pNRC200.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 1.
PE 3: Inferred from homology;
KW DNA-binding; Plasmid; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..186
FT /note="TATA-box-binding protein B"
FT /id="PRO_0000154000"
FT REPEAT 10..86
FT /note="1"
FT REPEAT 101..179
FT /note="2"
SQ SEQUENCE 186 AA; 19938 MW; 40F54B2CCAF29C97 CRC64;
MSTLADTIHI ENVVASSDLG QELALDQLST DLPGAEYNPE DFPGVVYRLQ EPKSATLIFR
SGKVVCTGAK SVDDVHEALG IVFGDIRELG IDVTSNPPIE VQNIVSSASL EQSLNLNAIA
IGLGLEQIEY EPEQFPGLVY RLDDPDVVVL LFGSGKLVIT GGQNPDEAEQ ALAHVQDRLT
ELGLLD
