ID   TBPC_HALSA              Reviewed;         181 AA.
AC   O52004;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=TATA-box-binding protein C;
DE   AltName: Full=Box A-binding protein C;
DE            Short=BAP C;
DE   AltName: Full=TATA sequence-binding protein C;
DE            Short=TBP C;
DE   AltName: Full=TATA-box factor C;
GN   Name=tbpC1; OrderedLocusNames=VNG_5142G;
GN   and
GN   Name=tbpC2; OrderedLocusNames=VNG_6140G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OG   Plasmid pNRC100, and Plasmid pNRC200.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1; PLASMID=pNRC100;
RX   PubMed=9847077; DOI=10.1101/gr.8.11.1131;
RA   Ng W.V., Ciufo S.A., Smith T.M., Bumgarner R.E., Baskin D., Faust J.,
RA   Hall B., Loretz C., Seto J., Slagel J., Hood L., DasSarma S.;
RT   "Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid
RT   or minichromosome?";
RL   Genome Res. 8:1131-1141(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1; PLASMID=pNRC200;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR   EMBL; AF016485; AAC82884.1; -; Genomic_DNA.
DR   EMBL; AE004438; AAG20813.1; -; Genomic_DNA.
DR   PIR; T08317; T08317.
DR   RefSeq; WP_010890481.1; NZ_BK010831.1.
DR   AlphaFoldDB; O52004; -.
DR   SMR; O52004; -.
DR   EnsemblBacteria; AAC82884; AAC82884; AAC82884.
DR   EnsemblBacteria; AAG20813; AAG20813; VNG_6140G.
DR   GeneID; 5954664; -.
DR   KEGG; hal:tbpC; -.
DR   KEGG; hal:VNG_6140G; -.
DR   PATRIC; fig|64091.14.peg.2173; -.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   InParanoid; O52004; -.
DR   OMA; CCTYEPE; -.
DR   OrthoDB; 83880at2157; -.
DR   PhylomeDB; O52004; -.
DR   Proteomes; UP000000554; Plasmid pNRC100.
DR   Proteomes; UP000000554; Plasmid pNRC200.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
PE   3: Inferred from homology;
KW   DNA-binding; Plasmid; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..181
FT                   /note="TATA-box-binding protein C"
FT                   /id="PRO_0000154001"
FT   REPEAT          5..83
FT                   /note="1"
FT   REPEAT          99..177
FT                   /note="2"
SQ   SEQUENCE   181 AA;  19761 MW;  A1DF9C60A17F0FBD CRC64;
     MTVEIANIVG SGDLGVELDV EPLEADLSTP YSEYDPSNYH GLYVRLEENG PLITVYRSGK
     YIITGCASME SLHETNEEFL GMLADLGVTE EDTQTGFTVE NVVCTAMLDE LVSLNALAIG
     LGLEVTEYEP EQFPGLVYRP EEIGAVLLVF ANGKMVITGA KDTETAESAY EYFQSKVQEL
     V