ID   TBPD_HALSA              Reviewed;         186 AA.
AC   O52018;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=TATA-box-binding protein D;
DE   AltName: Full=Box A-binding protein D;
DE            Short=BAP D;
DE   AltName: Full=TATA sequence-binding protein D;
DE            Short=TBP D;
DE   AltName: Full=TATA-box factor D;
GN   Name=tbpD; OrderedLocusNames=VNG_5163G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OG   Plasmid pNRC100.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=9847077; DOI=10.1101/gr.8.11.1131;
RA   Ng W.V., Ciufo S.A., Smith T.M., Bumgarner R.E., Baskin D., Faust J.,
RA   Hall B., Loretz C., Seto J., Slagel J., Hood L., DasSarma S.;
RT   "Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid
RT   or minichromosome?";
RL   Genome Res. 8:1131-1141(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR   EMBL; AF016485; AAC82898.1; -; Genomic_DNA.
DR   PIR; T08331; T08331.
DR   RefSeq; WP_010890467.1; NZ_BK010830.1.
DR   AlphaFoldDB; O52018; -.
DR   SMR; O52018; -.
DR   EnsemblBacteria; AAC82898; AAC82898; AAC82898.
DR   GeneID; 5954680; -.
DR   KEGG; hal:tbpD; -.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   InParanoid; O52018; -.
DR   OMA; FHFKIAD; -.
DR   OrthoDB; 83880at2157; -.
DR   PhylomeDB; O52018; -.
DR   Proteomes; UP000000554; Plasmid pNRC100.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
PE   3: Inferred from homology;
KW   DNA-binding; Plasmid; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..186
FT                   /note="TATA-box-binding protein D"
FT                   /id="PRO_0000154002"
FT   REPEAT          10..86
FT                   /note="1"
FT   REPEAT          101..179
FT                   /note="2"
SQ   SEQUENCE   186 AA;  19881 MW;  4F7B9608102699F4 CRC64;
     MSTLTDTIQI ENVVASTDLS QELALEQLAT DLPGAEYNPG DFPGVIYRLD DPKSATLIFD
     SGKAVCTGAQ SVDDVHDAIS IVVEDLRDLG IDIPPSPPVH VQNIVCSGSL DQDLNLNAIA
     IGLGLEDVEY EPEQFPGLVY RLNDPDVVVL LFGSGKLVIT GGSNPDDAHH ALEIIHERLT
     DLGLLE