TBPE_HALSA
ID TBPE_HALSA Reviewed; 186 AA.
AC Q9HN56;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=TATA-box-binding protein E;
DE AltName: Full=Box A-binding protein E;
DE Short=BAP E;
DE AltName: Full=TATA sequence-binding protein E;
DE Short=TBP E;
DE AltName: Full=TATA-box factor E;
GN Name=tbpE; OrderedLocusNames=VNG_2243G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; AE004437; AAG20365.1; -; Genomic_DNA.
DR PIR; A84375; A84375.
DR RefSeq; WP_010903666.1; NC_002607.1.
DR AlphaFoldDB; Q9HN56; -.
DR SMR; Q9HN56; -.
DR STRING; 64091.VNG_2243G; -.
DR PaxDb; Q9HN56; -.
DR EnsemblBacteria; AAG20365; AAG20365; VNG_2243G.
DR GeneID; 5953303; -.
DR GeneID; 62887526; -.
DR KEGG; hal:VNG_2243G; -.
DR PATRIC; fig|64091.14.peg.1725; -.
DR HOGENOM; CLU_060161_4_3_2; -.
DR InParanoid; Q9HN56; -.
DR OMA; NCEYEPE; -.
DR OrthoDB; 83880at2157; -.
DR PhylomeDB; Q9HN56; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..186
FT /note="TATA-box-binding protein E"
FT /id="PRO_0000154003"
FT REPEAT 10..86
FT /note="1"
FT REPEAT 101..179
FT /note="2"
SQ SEQUENCE 186 AA; 20307 MW; 5D8BC9E6D8E5AF14 CRC64;
MTDPKETINI ENVVASTGIG QELDLQSVAM DLEGADYDPE QFPGLVYRTQ DPKSAALIFR
SGKIVCTGAK STDDVHESLR IVFDKLRELS IKVEDDPEIV VQNIVTSADL GRQLNLNAIA
IGLGLENIEY EPEQFPGLVY RLDDPEVVAL LFGSGKLVIT GGKEPKDAEH AVDKITSRLE
ELGLLD
