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TBPL1_CHICK
ID   TBPL1_CHICK             Reviewed;         183 AA.
AC   Q9YGV8;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=TATA box-binding protein-like 1;
DE            Short=TBP-like 1;
DE   AltName: Full=TBP-like factor;
GN   Name=TBPL1; Synonyms=TBP;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=B-cell;
RX   PubMed=10454611; DOI=10.1093/nar/27.15.3146;
RA   Shimada M., Ohbayashi T., Ishida M., Nakadai T., Makino Y., Aoki T.,
RA   Kawata T., Suzuki T., Matsuda Y., Tamura T.-A.;
RT   "Analysis of the chicken TBP-like protein (tlp) gene: evidence for a
RT   striking conservation of vertebrate TLPs and for a close relationship
RT   between vertebrate tbp and tlp genes.";
RL   Nucleic Acids Res. 27:3146-3152(1999).
CC   -!- FUNCTION: Part of a specialized transcription system that mediates the
CC       transcription of most ribosomal proteins through the 5'-TCT-3' motif
CC       which is a core promoter element at these genes. Seems to also mediate
CC       the transcription of NF1. Does not bind the TATA box (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Binds TFIIA and TFIIB. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Present in the brain, heart, liver and gizzard.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR   EMBL; AB024489; BAA75886.1; -; mRNA.
DR   RefSeq; NP_990086.1; NM_204755.1.
DR   RefSeq; XP_015139496.1; XM_015284010.1.
DR   RefSeq; XP_015139497.1; XM_015284011.1.
DR   RefSeq; XP_015139498.1; XM_015284012.1.
DR   AlphaFoldDB; Q9YGV8; -.
DR   SMR; Q9YGV8; -.
DR   STRING; 9031.ENSGALP00000022616; -.
DR   PaxDb; Q9YGV8; -.
DR   Ensembl; ENSGALT00000051224; ENSGALP00000055961; ENSGALG00000013981.
DR   GeneID; 395517; -.
DR   KEGG; gga:395517; -.
DR   CTD; 9519; -.
DR   VEuPathDB; HostDB:geneid_395517; -.
DR   eggNOG; KOG3302; Eukaryota.
DR   GeneTree; ENSGT00940000155712; -.
DR   HOGENOM; CLU_060161_4_1_1; -.
DR   InParanoid; Q9YGV8; -.
DR   OMA; NCEYEPE; -.
DR   OrthoDB; 1219067at2759; -.
DR   PhylomeDB; Q9YGV8; -.
DR   TreeFam; TF300102; -.
DR   PRO; PR:Q9YGV8; -.
DR   Proteomes; UP000000539; Chromosome 3.
DR   Bgee; ENSGALG00000013981; Expressed in spermatid and 14 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0001673; C:male germ cell nucleus; IEA:Ensembl.
DR   GO; GO:0005672; C:transcription factor TFIIA complex; IEA:Ensembl.
DR   GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:Ensembl.
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007289; P:spermatid nucleus differentiation; IEA:Ensembl.
DR   CDD; cd04517; TLF; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR015445; TBP-like.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
PE   2: Evidence at transcript level;
KW   Cytoplasm; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..183
FT                   /note="TATA box-binding protein-like 1"
FT                   /id="PRO_0000153994"
SQ   SEQUENCE   183 AA;  20533 MW;  420BAC48946FB9CF CRC64;
     MDADSDVALD ILITNVVCVF RTRCHLNLRK IALEGANVIY KRDVGKVLMK LRKPRITATI
     WSSGKVICTG ATSEEEAKFG ARRLARCLQK LGFQVIFTDF KVVNVLAVCN MPFEIRLPEF
     TKNNRPHASY EPELHPAVCY RIKTLRATLQ IFSTGSITVT GPNVKAVASA VEQIYPFVFE
     SRK
 
 
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