TBPL1_CHICK
ID TBPL1_CHICK Reviewed; 183 AA.
AC Q9YGV8;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=TATA box-binding protein-like 1;
DE Short=TBP-like 1;
DE AltName: Full=TBP-like factor;
GN Name=TBPL1; Synonyms=TBP;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=B-cell;
RX PubMed=10454611; DOI=10.1093/nar/27.15.3146;
RA Shimada M., Ohbayashi T., Ishida M., Nakadai T., Makino Y., Aoki T.,
RA Kawata T., Suzuki T., Matsuda Y., Tamura T.-A.;
RT "Analysis of the chicken TBP-like protein (tlp) gene: evidence for a
RT striking conservation of vertebrate TLPs and for a close relationship
RT between vertebrate tbp and tlp genes.";
RL Nucleic Acids Res. 27:3146-3152(1999).
CC -!- FUNCTION: Part of a specialized transcription system that mediates the
CC transcription of most ribosomal proteins through the 5'-TCT-3' motif
CC which is a core promoter element at these genes. Seems to also mediate
CC the transcription of NF1. Does not bind the TATA box (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Binds TFIIA and TFIIB. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Present in the brain, heart, liver and gizzard.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; AB024489; BAA75886.1; -; mRNA.
DR RefSeq; NP_990086.1; NM_204755.1.
DR RefSeq; XP_015139496.1; XM_015284010.1.
DR RefSeq; XP_015139497.1; XM_015284011.1.
DR RefSeq; XP_015139498.1; XM_015284012.1.
DR AlphaFoldDB; Q9YGV8; -.
DR SMR; Q9YGV8; -.
DR STRING; 9031.ENSGALP00000022616; -.
DR PaxDb; Q9YGV8; -.
DR Ensembl; ENSGALT00000051224; ENSGALP00000055961; ENSGALG00000013981.
DR GeneID; 395517; -.
DR KEGG; gga:395517; -.
DR CTD; 9519; -.
DR VEuPathDB; HostDB:geneid_395517; -.
DR eggNOG; KOG3302; Eukaryota.
DR GeneTree; ENSGT00940000155712; -.
DR HOGENOM; CLU_060161_4_1_1; -.
DR InParanoid; Q9YGV8; -.
DR OMA; NCEYEPE; -.
DR OrthoDB; 1219067at2759; -.
DR PhylomeDB; Q9YGV8; -.
DR TreeFam; TF300102; -.
DR PRO; PR:Q9YGV8; -.
DR Proteomes; UP000000539; Chromosome 3.
DR Bgee; ENSGALG00000013981; Expressed in spermatid and 14 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0001673; C:male germ cell nucleus; IEA:Ensembl.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:Ensembl.
DR GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:Ensembl.
DR GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR GO; GO:0006235; P:dTTP biosynthetic process; IEA:Ensembl.
DR GO; GO:0007289; P:spermatid nucleus differentiation; IEA:Ensembl.
DR CDD; cd04517; TLF; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR015445; TBP-like.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
PE 2: Evidence at transcript level;
KW Cytoplasm; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..183
FT /note="TATA box-binding protein-like 1"
FT /id="PRO_0000153994"
SQ SEQUENCE 183 AA; 20533 MW; 420BAC48946FB9CF CRC64;
MDADSDVALD ILITNVVCVF RTRCHLNLRK IALEGANVIY KRDVGKVLMK LRKPRITATI
WSSGKVICTG ATSEEEAKFG ARRLARCLQK LGFQVIFTDF KVVNVLAVCN MPFEIRLPEF
TKNNRPHASY EPELHPAVCY RIKTLRATLQ IFSTGSITVT GPNVKAVASA VEQIYPFVFE
SRK