ID   TBPL2_TAKRU             Reviewed;         322 AA.
AC   Q6SJ94;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=TATA box-binding protein-like 2 {ECO:0000303|PubMed:17570761};
DE            Short=TBP-like 2 {ECO:0000303|PubMed:17570761};
DE   AltName: Full=TATA box-binding protein-related factor 3 {ECO:0000303|PubMed:14634207};
DE            Short=TBP-related factor 3 {ECO:0000303|PubMed:14634207};
GN   Name=tbpl2 {ECO:0000303|PubMed:17570761};
GN   Synonyms=tbp2 {ECO:0000250|UniProtKB:Q5UE94},
GN   trf3 {ECO:0000312|EMBL:AAR24283.1};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033;
RN   [1] {ECO:0000312|EMBL:AAR24283.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Ovary {ECO:0000312|EMBL:AAR24283.1};
RX   PubMed=14634207; DOI=10.1073/pnas.2036440100;
RA   Persengiev S.P., Zhu X., Dixit B.L., Maston G.A., Kittler E.L.W.,
RA   Green M.R.;
RT   "TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific
RT   and widely expressed.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:14887-14891(2003).
RN   [2] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Fugu genome sequencing consortium;
RL   Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000305, ECO:0000312|EMBL:DAA06036.1}
RP   IDENTIFICATION.
RX   PubMed=17570761; DOI=10.1089/dna.2006.0527;
RA   Di Pietro C., Ragusa M., Duro L., Guglielmino M.R., Barbagallo D.,
RA   Carnemolla A., Lagana A., Buffa P., Angelica R., Rinaldi A., Calafato M.S.,
RA   Milicia I., Caserta C., Giugno R., Pulvirenti A., Giunta V., Rapisarda A.,
RA   Di Pietro V., Grillo A., Messina A., Ferro A., Grzeschik K.H., Purrello M.;
RT   "Genomics, evolution, and expression of TBPL2, a member of the TBP
RT   family.";
RL   DNA Cell Biol. 26:369-385(2007).
CC   -!- FUNCTION: TATA box-binding transcription factor. Members of the TBP
CC       family are differentially required to regulate transcription and
CC       development during early embryogenesis (By similarity).
CC       {ECO:0000250|UniProtKB:Q5UE94}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q5UE94}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255}.
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DR   EMBL; AY457925; AAR24283.1; -; mRNA.
DR   EMBL; CAAB01000338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BK005776; DAA06036.1; -; mRNA.
DR   RefSeq; NP_001027845.1; NM_001032673.1.
DR   RefSeq; XP_011617974.1; XM_011619672.1.
DR   AlphaFoldDB; Q6SJ94; -.
DR   SMR; Q6SJ94; -.
DR   Ensembl; ENSTRUT00000023437; ENSTRUP00000023340; ENSTRUG00000009283.
DR   GeneID; 446042; -.
DR   KEGG; tru:446042; -.
DR   CTD; 387332; -.
DR   GeneTree; ENSGT00940000159561; -.
DR   InParanoid; Q6SJ94; -.
DR   OrthoDB; 1219067at2759; -.
DR   Proteomes; UP000005226; Chromosome 2.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:Ensembl.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:Ensembl.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; ISS:UniProtKB.
DR   GO; GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; ISS:UniProtKB.
DR   CDD; cd04516; TBP_eukaryotes; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   InterPro; IPR033710; TBP_eukaryotic.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 2.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..322
FT                   /note="TATA box-binding protein-like 2"
FT                   /id="PRO_0000349149"
FT   REGION          31..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   322 AA;  35721 MW;  FBFCDABC77AEE962 CRC64;
     MDESALERYF EDSIANDSGF ILEEELGLHS PALSSTQDST YLSGRAGPSR ESGAELDLSF
     LPDDLSTQEE LGHHDNTAQA EDRAVSQDSA VCLDYDSQNS ATPAATFDQQ NPSLLGGGVH
     NSPFYSMTPM TPMTPMTPVT ERSGIIPQLQ NIVSTVNLGC PLDLKFIALQ ARNAEYNPKR
     FAAVIMRIRE PRTTALIFSS GKMVCTGAKS EEQSRLAARK YARVVQKLGF PARFMDFKIQ
     NMVASCDVCF PIRLEGLVLT HQQFSSYEPE LFPGLIYRMV KPRIVLLIFV SGKVVLTGAK
     ERAEIYEAFE NIYPILRGFR KQ