ID   TBP_AERPE               Reviewed;         203 AA.
AC   Q9YAT1;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 3.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=TATA-box-binding protein;
DE   AltName: Full=Box A-binding protein;
DE            Short=BAP;
DE   AltName: Full=TATA sequence-binding protein;
DE            Short=TBP;
DE   AltName: Full=TATA-box factor;
GN   Name=tbp; OrderedLocusNames=APE_1862.1;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR   EMBL; BA000002; BAA80867.2; -; Genomic_DNA.
DR   PIR; F72572; F72572.
DR   AlphaFoldDB; Q9YAT1; -.
DR   SMR; Q9YAT1; -.
DR   STRING; 272557.APE_1862.1; -.
DR   EnsemblBacteria; BAA80867; BAA80867; APE_1862.1.
DR   KEGG; ape:APE_1862.1; -.
DR   PATRIC; fig|272557.25.peg.1248; -.
DR   eggNOG; arCOG01764; Archaea.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..203
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_0000153997"
FT   REPEAT          25..101
FT                   /note="1"
FT   REPEAT          116..192
FT                   /note="2"
SQ   SEQUENCE   203 AA;  22645 MW;  796AF8DCDE0321DE CRC64;
     MSEEISFVKE IDTGVEGLPK PEVKIENIVA TVILENQLDL NLIETKIQDV DYNPDQFPGL
     VYRLESPRVT VLIFKSGKMV ITGAKSINQL IHVVKKLLKA FADQGIPISG KPQIQIQNIV
     ASANLKVYID LEKAALEFEN SLYEPEQFPG LIYRMDEPRV VMLIFSSGKM VITGAKMENE
     VYDAVKKVAR KLKEADAIIG IAE