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TBP_ARCFU
ID   TBP_ARCFU               Reviewed;         183 AA.
AC   O29874;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=TATA-box-binding protein;
DE   AltName: Full=Box A-binding protein;
DE            Short=BAP;
DE   AltName: Full=TATA sequence-binding protein;
DE            Short=TBP;
DE   AltName: Full=TATA-box factor;
GN   Name=tbp; OrderedLocusNames=AF_0373;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR   EMBL; AE000782; AAB90862.1; -; Genomic_DNA.
DR   PIR; E69296; E69296.
DR   RefSeq; WP_010877880.1; NC_000917.1.
DR   AlphaFoldDB; O29874; -.
DR   SMR; O29874; -.
DR   STRING; 224325.AF_0373; -.
DR   EnsemblBacteria; AAB90862; AAB90862; AF_0373.
DR   GeneID; 24793912; -.
DR   KEGG; afu:AF_0373; -.
DR   eggNOG; arCOG01764; Archaea.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   OMA; NCEYEPE; -.
DR   OrthoDB; 83880at2157; -.
DR   PhylomeDB; O29874; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..183
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_0000153998"
FT   REPEAT          8..84
FT                   /note="1"
FT   REPEAT          99..177
FT                   /note="2"
SQ   SEQUENCE   183 AA;  20135 MW;  255C5C05BBE3D8A3 CRC64;
     MQDYKIKIEN VVASTQIGEN IDLNKISREI KDSEYKPKQF PGLVLRTKEP KAAALVFRSG
     KVVCTGSKSV EDARRAVKQI VKMLKEIGIS VIDEPEVKVQ NIVASADLGV DLNLNAIAIG
     LGLENIEYEP EQFPGLVYRL DNPRVVVLIF GSGKMVVTGG KSPEDARKAV ERISEELRTL
     GLM
 
 
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