ID   TBP_CENSY               Reviewed;         182 AA.
AC   O74045; A0RWT5;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=TATA-box-binding protein;
DE   AltName: Full=Box A-binding protein;
DE            Short=BAP;
DE   AltName: Full=TATA sequence-binding protein;
DE            Short=TBP;
DE   AltName: Full=TATA-box factor;
GN   Name=tbp; Synonyms=TF2D; OrderedLocusNames=CENSYa_1178;
OS   Cenarchaeum symbiosum (strain A).
OC   Archaea; Thaumarchaeota; Cenarchaeales; Cenarchaeaceae; Cenarchaeum.
OX   NCBI_TaxID=414004;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A;
RX   PubMed=9748430; DOI=10.1128/jb.180.19.5003-5009.1998;
RA   Schleper C., Delong E.F., Preston C.M., Feldman R.A., Wu K.-Y.,
RA   Swanson R.V.;
RT   "Genomic analysis reveals chromosomal variation in natural populations of
RT   the uncultured psychrophilic archaeon Cenarchaeum symbiosum.";
RL   J. Bacteriol. 180:5003-5009(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A;
RX   PubMed=17114289; DOI=10.1073/pnas.0608549103;
RA   Hallam S.J., Konstantinidis K.T., Putnam N., Schleper C., Watanabe Y.,
RA   Sugahara J., Preston C., de la Torre J., Richardson P.M., DeLong E.F.;
RT   "Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum
RT   symbiosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:18296-18301(2006).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR   EMBL; AF083071; AAC62688.1; -; Genomic_DNA.
DR   EMBL; DP000238; ABK77802.1; -; Genomic_DNA.
DR   AlphaFoldDB; O74045; -.
DR   SMR; O74045; -.
DR   STRING; 414004.CENSYa_1178; -.
DR   EnsemblBacteria; ABK77802; ABK77802; CENSYa_1178.
DR   KEGG; csy:CENSYa_1178; -.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   Proteomes; UP000000758; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 1.
DR   PRINTS; PR00686; TIFACTORIID.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..182
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_0000153999"
FT   REPEAT          10..87
FT                   /note="1"
FT   REPEAT          102..177
FT                   /note="2"
SQ   SEQUENCE   182 AA;  19534 MW;  75800EA6676375CE CRC64;
     MLDPRTRPRV VNVVSTSDLV QRVSAKKMAA MPCCMYDEAV YGGRCGYIKT PGMQGRVTVF
     ISGKMISVGA RSVRASFGQL HEARLHLVRN GAAGDCKIRP VVRNIVATVD AGRNVPIDRI
     SSRMPGAVYD PGSFPGMILK GLDSCSFLVF ASGKMVIAGA KSPDELRRSS FDLLTRLNNA
     GA