ID   TBP_HALMA               Reviewed;         186 AA.
AC   Q5V470;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=TATA-box-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=Box A-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=BAP {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA sequence-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=TBP {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA-box factor {ECO:0000255|HAMAP-Rule:MF_00408};
GN   Name=tbp {ECO:0000255|HAMAP-Rule:MF_00408}; OrderedLocusNames=rrnAC0681;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00408}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY596297; AAV45682.1; -; Genomic_DNA.
DR   RefSeq; WP_004516850.1; NZ_CP039138.1.
DR   AlphaFoldDB; Q5V470; -.
DR   SMR; Q5V470; -.
DR   STRING; 272569.rrnAC0681; -.
DR   EnsemblBacteria; AAV45682; AAV45682; rrnAC0681.
DR   GeneID; 40151721; -.
DR   GeneID; 64822650; -.
DR   KEGG; hma:rrnAC0681; -.
DR   PATRIC; fig|272569.17.peg.1431; -.
DR   eggNOG; arCOG01764; Archaea.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   OMA; NCEYEPE; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..186
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_1000049878"
FT   REPEAT          10..86
FT                   /note="1"
FT   REPEAT          101..179
FT                   /note="2"
SQ   SEQUENCE   186 AA;  20161 MW;  EBB0E0D265B86C8C CRC64;
     MVDPKESIDI ENVVASTGIG QELDLESVAM DLEGADYDPE QFPGLVYRTQ DPKSAALIFR
     SGKIVCTGAK STDDVHQSLR IVFDKLRDLN IQVDDDPEIV VQNIVSSADL GSSLNLNAIA
     IGLGLENIEY EPEQFPGLVY RLDEPDVVAL LFGSGKLVVT GGKRKEDAEE AVDTIVERLS
     DLGLLD