TBP_METMP
ID TBP_METMP Reviewed; 181 AA.
AC Q6M0L3;
DT 21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=TATA-box-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=Box A-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=BAP {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA sequence-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=TBP {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA-box factor {ECO:0000255|HAMAP-Rule:MF_00408};
GN Name=tbp {ECO:0000255|HAMAP-Rule:MF_00408}; OrderedLocusNames=MMP0257;
OS Methanococcus maripaludis (strain S2 / LL).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanococcaceae; Methanococcus.
OX NCBI_TaxID=267377;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2 / LL;
RX PubMed=15466049; DOI=10.1128/jb.186.20.6956-6969.2004;
RA Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D.,
RA Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA Olson M.V., Leigh J.A.;
RT "Complete genome sequence of the genetically tractable hydrogenotrophic
RT methanogen Methanococcus maripaludis.";
RL J. Bacteriol. 186:6956-6969(2004).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC Rule:MF_00408}.
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DR EMBL; BX950229; CAF29813.1; -; Genomic_DNA.
DR RefSeq; WP_011170201.1; NC_005791.1.
DR AlphaFoldDB; Q6M0L3; -.
DR SMR; Q6M0L3; -.
DR STRING; 267377.MMP0257; -.
DR EnsemblBacteria; CAF29813; CAF29813; MMP0257.
DR GeneID; 41278678; -.
DR KEGG; mmp:MMP0257; -.
DR PATRIC; fig|267377.15.peg.259; -.
DR eggNOG; arCOG01764; Archaea.
DR HOGENOM; CLU_060161_4_3_2; -.
DR OMA; NCEYEPE; -.
DR OrthoDB; 83880at2157; -.
DR BioCyc; MMAR267377:MMP_RS01390-MON; -.
DR Proteomes; UP000000590; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..181
FT /note="TATA-box-binding protein"
FT /id="PRO_0000154013"
FT REPEAT 7..83
FT /note="1"
FT REPEAT 98..173
FT /note="2"
SQ SEQUENCE 181 AA; 20113 MW; C1790A4A4C9A4396 CRC64;
MEPEIKVVNV VVSTQIGTDI DLEYAADILD NAEYEPEQFP GLVCRLSEPK VALLIFRSGK
LNCTGARCKE DAVIAINKIV KELKEAGMDL IDNPEVKVQN MVATTELGME PNLDDISTLE
CTEYEPEQFP GLVYRLSEPK VVVLIFGSGK VVITGLKVIE DAYIAFDKIS KTLKELEEEL
Y