TBP_METTP
ID TBP_METTP Reviewed; 183 AA.
AC A0B5H8;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=TATA-box-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=Box A-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=BAP {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA sequence-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=TBP {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA-box factor {ECO:0000255|HAMAP-Rule:MF_00408};
GN Name=tbp {ECO:0000255|HAMAP-Rule:MF_00408}; OrderedLocusNames=Mthe_0152;
OS Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 /
OS PT) (Methanosaeta thermophila).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanotrichales; Methanotrichaceae; Methanothrix.
OX NCBI_TaxID=349307;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6194 / JCM 14653 / NBRC 101360 / PT;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Smith K.S., Ingram-Smith C., Richardson P.;
RT "Complete sequence of Methanosaeta thermophila PT.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC Rule:MF_00408}.
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DR EMBL; CP000477; ABK13952.1; -; Genomic_DNA.
DR AlphaFoldDB; A0B5H8; -.
DR SMR; A0B5H8; -.
DR STRING; 349307.Mthe_0152; -.
DR EnsemblBacteria; ABK13952; ABK13952; Mthe_0152.
DR KEGG; mtp:Mthe_0152; -.
DR HOGENOM; CLU_060161_4_3_2; -.
DR OMA; NCEYEPE; -.
DR Proteomes; UP000000674; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..183
FT /note="TATA-box-binding protein"
FT /id="PRO_1000049883"
FT REPEAT 7..83
FT /note="1"
FT REPEAT 99..177
FT /note="2"
SQ SEQUENCE 183 AA; 20135 MW; 514C4AF603D14630 CRC64;
MESTINIENV VASTKLADEF DLVKIESELE GAEYNKEKFP GLVYRVKSPK AAFLIFTSGK
VVCTGAKNVE DVRTVITNMA RTLKSIGFDN INLEPEIHVQ NIVASADLKT DLNLNAIALG
LGLENIEYEP EQFPGLVYRI KQPKVVVLIF SSGKLVVTGG KSPEECEEGV RIVRQQLENL
GLL