TBP_PYRAB
ID TBP_PYRAB Reviewed; 191 AA.
AC Q9V024; G8ZID9;
DT 21-FEB-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=TATA-box-binding protein;
DE AltName: Full=Box A-binding protein;
DE Short=BAP;
DE AltName: Full=TATA sequence-binding protein;
DE Short=TBP;
DE AltName: Full=TATA-box factor;
GN Name=tbp; OrderedLocusNames=PYRAB09740; ORFNames=PAB1726;
OS Pyrococcus abyssi (strain GE5 / Orsay).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=272844;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GE5 / Orsay;
RX PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA Weissenbach J., Zivanovic Y., Forterre P.;
RT "An integrated analysis of the genome of the hyperthermophilic archaeon
RT Pyrococcus abyssi.";
RL Mol. Microbiol. 47:1495-1512(2003).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=GE5 / Orsay;
RX PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA Gao J., Wang J.;
RT "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT Pyrococcus furiosus DSM 3638.";
RL Curr. Microbiol. 64:118-129(2012).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; AJ248286; CAB49882.1; -; Genomic_DNA.
DR EMBL; HE613800; CCE70380.1; -; Genomic_DNA.
DR PIR; E75072; E75072.
DR RefSeq; WP_010868091.1; NC_000868.1.
DR AlphaFoldDB; Q9V024; -.
DR SMR; Q9V024; -.
DR STRING; 272844.PAB1726; -.
DR EnsemblBacteria; CAB49882; CAB49882; PAB1726.
DR GeneID; 1496324; -.
DR KEGG; pab:PAB1726; -.
DR PATRIC; fig|272844.11.peg.1026; -.
DR eggNOG; arCOG01764; Archaea.
DR HOGENOM; CLU_060161_4_3_2; -.
DR OMA; NCEYEPE; -.
DR OrthoDB; 83880at2157; -.
DR PhylomeDB; Q9V024; -.
DR Proteomes; UP000000810; Chromosome.
DR Proteomes; UP000009139; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 3: Inferred from homology;
KW DNA-binding; Repeat; Transcription; Transcription regulation.
FT CHAIN 1..191
FT /note="TATA-box-binding protein"
FT /id="PRO_0000154017"
FT REPEAT 11..87
FT /note="1"
FT REPEAT 102..178
FT /note="2"
SQ SEQUENCE 191 AA; 21410 MW; B997B5ED96F8DCB4 CRC64;
MVDTNNVKLR IENIVASVDL FAQLDLEKVL DICPNSKYNP EEFPGIICRF DDPKVALLIF
SSGKLVVTGA KSIHDIERAV AKLIEKLKGI GVKFKRAPLI DIQNMVFSGD IGREFNLDNV
ALTLPNCEYE PEQFPGVIYR VKDPRAVILL FSSGKIVCSG AKSEADAWEA VRKLLRELEK
YGLIEEEEEE L
