ID   TBP_PYRAE               Reviewed;         199 AA.
AC   Q8ZVR0;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=TATA-box-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=Box A-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=BAP {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA sequence-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=TBP {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA-box factor {ECO:0000255|HAMAP-Rule:MF_00408};
GN   Name=tbp {ECO:0000255|HAMAP-Rule:MF_00408}; OrderedLocusNames=PAE2164;
OS   Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS   104966 / NBRC 100827 / IM2).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=178306;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2;
RX   PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00408}.
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DR   EMBL; AE009441; AAL63996.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8ZVR0; -.
DR   SMR; Q8ZVR0; -.
DR   STRING; 178306.PAE2164; -.
DR   EnsemblBacteria; AAL63996; AAL63996; PAE2164.
DR   KEGG; pai:PAE2164; -.
DR   PATRIC; fig|178306.9.peg.1602; -.
DR   eggNOG; arCOG01764; Archaea.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   InParanoid; Q8ZVR0; -.
DR   OMA; NCEYEPE; -.
DR   Proteomes; UP000002439; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 2.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..199
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_0000154018"
FT   REPEAT          10..86
FT                   /note="1"
FT   REPEAT          101..177
FT                   /note="2"
SQ   SEQUENCE   199 AA;  22095 MW;  0D5F0A071FF1725E CRC64;
     MSSKGPSYRI ENIVATVNLG VELDLEQLAE RLTMAEYNPD QFPGLILRLT KPRISALIFR
     TGKMVCTGAK NEEDLKNAVR ALVKLLKDHG ADVPFDPEVQ IQNIVASGNL HAEVDLEQAV
     LMLENAMYEP EQFPGLIYRM SSPRVVILIF GSGKIVCTGA KSEKDVATAV QKLYNQLKEL
     GVLYVEEGGE ELEEFEEEL