TBP_PYRFU
ID TBP_PYRFU Reviewed; 191 AA.
AC P62000; Q57050;
DT 07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2004, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=TATA-box-binding protein;
DE AltName: Full=Box A-binding protein;
DE Short=BAP;
DE AltName: Full=TATA sequence-binding protein;
DE Short=TBP;
DE AltName: Full=TATA-box factor;
GN Name=tbp; OrderedLocusNames=PF1295;
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Scott R.A., Zeng Q., Lewis L.M., Colangelo C.M.;
RL Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; U48392; AAA93368.1; -; Genomic_DNA.
DR EMBL; AE009950; AAL81419.1; -; Genomic_DNA.
DR PIR; T47230; T47230.
DR RefSeq; WP_011012439.1; NC_018092.1.
DR AlphaFoldDB; P62000; -.
DR SMR; P62000; -.
DR MINT; P62000; -.
DR STRING; 186497.PF1295; -.
DR PRIDE; P62000; -.
DR EnsemblBacteria; AAL81419; AAL81419; PF1295.
DR GeneID; 41713099; -.
DR KEGG; pfu:PF1295; -.
DR PATRIC; fig|186497.12.peg.1358; -.
DR eggNOG; arCOG01764; Archaea.
DR HOGENOM; CLU_060161_4_3_2; -.
DR OMA; NCEYEPE; -.
DR OrthoDB; 83880at2157; -.
DR PhylomeDB; P62000; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..191
FT /note="TATA-box-binding protein"
FT /id="PRO_0000154019"
FT REPEAT 11..87
FT /note="1"
FT REPEAT 102..178
FT /note="2"
SQ SEQUENCE 191 AA; 21312 MW; B371491BF9282972 CRC64;
MVDMSKVKLR IENIVASVDL FAQLDLEKVL DLCPNSKYNP EEFPGIICHL DDPKVALLIF
SSGKLVVTGA KSVQDIERAV AKLAQKLKSI GVKFKRAPQI DVQNMVFSGD IGREFNLDVV
ALTLPNCEYE PEQFPGVIYR VKEPKSVILL FSSGKIVCSG AKSEADAWEA VRKLLRELDK
YGLLEEEEEE L
