TBP_PYRHO
ID TBP_PYRHO Reviewed; 191 AA.
AC O58737;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=TATA-box-binding protein;
DE AltName: Full=Box A-binding protein;
DE Short=BAP;
DE AltName: Full=TATA sequence-binding protein;
DE Short=TBP;
DE AltName: Full=TATA-box factor;
GN Name=tbp; OrderedLocusNames=PH1009;
OS Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS 100139 / OT-3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=70601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT "Complete sequence and gene organization of the genome of a hyper-
RT thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL DNA Res. 5:55-76(1998).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; BA000001; BAA30106.1; -; Genomic_DNA.
DR PIR; D71093; D71093.
DR RefSeq; WP_010885095.1; NC_000961.1.
DR AlphaFoldDB; O58737; -.
DR SMR; O58737; -.
DR STRING; 70601.3257423; -.
DR EnsemblBacteria; BAA30106; BAA30106; BAA30106.
DR GeneID; 1443330; -.
DR KEGG; pho:PH1009; -.
DR eggNOG; arCOG01764; Archaea.
DR OMA; NCEYEPE; -.
DR OrthoDB; 83880at2157; -.
DR Proteomes; UP000000752; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 3: Inferred from homology;
KW DNA-binding; Repeat; Transcription; Transcription regulation.
FT CHAIN 1..191
FT /note="TATA-box-binding protein"
FT /id="PRO_0000154020"
FT REPEAT 11..87
FT /note="1"
FT REPEAT 102..178
FT /note="2"
SQ SEQUENCE 191 AA; 21373 MW; 85E8AD2A0FADF589 CRC64;
MVDTSNVKLR IENIVASVDL FAQLDLEKVL DICPNSKYNP EEFPGIICRF DDPKVALLIF
SSGKLVVTGA KSIQDIERAV AKLIQKLKGI GVKFKRAPLI DVQNMVFSGD IGREFNLDNV
ALTLPNCEYE PEQFPGVIYR VKEPRAVILL FSSGKIVCSG AKSEADAWEA VRKLLRELEK
YGLIEEEEEE L
