ID   TBP_SACS2               Reviewed;         198 AA.
AC   P58178;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=TATA-box-binding protein;
DE   AltName: Full=Box A-binding protein;
DE            Short=BAP;
DE   AltName: Full=TATA sequence-binding protein;
DE            Short=TBP;
DE   AltName: Full=TATA-box factor;
GN   Name=tbp; Synonyms=tfiID; OrderedLocusNames=SSO0951;
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK41225.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE006641; AAK41225.1; ALT_INIT; Genomic_DNA.
DR   PIR; B90246; B90246.
DR   AlphaFoldDB; P58178; -.
DR   SMR; P58178; -.
DR   STRING; 273057.SSO0951; -.
DR   EnsemblBacteria; AAK41225; AAK41225; SSO0951.
DR   KEGG; sso:SSO0951; -.
DR   PATRIC; fig|273057.12.peg.947; -.
DR   eggNOG; arCOG01764; Archaea.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   InParanoid; P58178; -.
DR   OMA; NCEYEPE; -.
DR   PhylomeDB; P58178; -.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0140223; F:general transcription initiation factor activity; IBA:GO_Central.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 2.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..198
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_0000154026"
FT   REPEAT          14..90
FT                   /note="1"
FT   REPEAT          105..181
FT                   /note="2"
SQ   SEQUENCE   198 AA;  22309 MW;  231448D0B2B026D7 CRC64;
     MSNSAVSYKP IVNIENIVAT VTLEQSLDLY AMERSIPNIE YDPDQFPGLI FRLEQPKVTA
     LIFKSGKMVV TGAKSTEELI KAVKRIIKTL KKYGIKIVGK PKIQIQNIVA SANLHVNVNL
     DKAAFLLENN MYEPEQFPGL IFRMDDPRVV LLIFSSGKMV ITGAKREDEV SKAVKRIFDK
     LAELDCVKPI EEEEELEL