TBP_SACSH
ID TBP_SACSH Reviewed; 198 AA.
AC Q55031;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2001, sequence version 2.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=TATA-box-binding protein;
DE AltName: Full=Box A-binding protein;
DE Short=BAP;
DE AltName: Full=TATA sequence-binding protein;
DE Short=TBP;
DE AltName: Full=TATA-box factor;
GN Name=tbp;
OS Saccharolobus shibatae (Sulfolobus shibatae).
OC Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Saccharolobus.
OX NCBI_TaxID=2286;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
RX PubMed=7784182; DOI=10.1093/nar/23.10.1775;
RA Qureshi S.A., Baumann P.B., Rowlands T., Khoo B., Jackson S.P.;
RT "Cloning and functional analysis of the TATA binding protein from
RT Sulfolobus shibatae.";
RL Nucleic Acids Res. 23:1775-1781(1995).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR EMBL; U23419; AAC43403.1; -; Genomic_DNA.
DR PIR; S55311; S55311.
DR AlphaFoldDB; Q55031; -.
DR SMR; Q55031; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Repeat; Transcription; Transcription regulation.
FT CHAIN 1..198
FT /note="TATA-box-binding protein"
FT /id="PRO_0000154025"
FT REPEAT 14..90
FT /note="1"
FT REPEAT 105..181
FT /note="2"
SQ SEQUENCE 198 AA; 22341 MW; 55CF3917A7B163C3 CRC64;
MSNSAVSYKP IVNIENIVAT VTLEQSLDLY AMERSIPNIE YDPDQFPGLI FRLEQPKVTA
LIFKSGKMVV TGAKSTEELI KAVKRIIKTL KKYGIKIMGK PKIQIQNIVA SANLHVNVNL
DKAAFLLENN MYEPEQFPGL IFRMDDPRVV LLIFSSGKMV ITGAKREDEV SKAVKRIFDK
LAELDCVKPI EEEEELEL