ID   TBP_THECE               Reviewed;         189 AA.
AC   Q56253;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=TATA-box-binding protein;
DE   AltName: Full=Box A-binding protein;
DE            Short=BAP;
DE   AltName: Full=TATA sequence-binding protein;
DE            Short=TBP;
DE   AltName: Full=TATA-box factor;
GN   Name=tbp;
OS   Thermococcus celer.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=2264;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 35543 / DSM 2476 / JCM 8558 / Vu 13;
RX   PubMed=8183889; DOI=10.1073/pnas.91.10.4180;
RA   Marsh T.L., Reich C.I., Whitelock R.B., Olsen G.J.;
RT   "Transcription factor IID in the Archaea: sequences in the Thermococcus
RT   celer genome would encode a product closely related to the TATA-binding
RT   protein of eukaryotes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:4180-4184(1994).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000305}.
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DR   EMBL; U04932; AAA73412.1; -; Unassigned_DNA.
DR   AlphaFoldDB; Q56253; -.
DR   SMR; Q56253; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 2.
PE   3: Inferred from homology;
KW   DNA-binding; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..189
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_0000154029"
FT   REPEAT          8..84
FT                   /note="1"
FT   REPEAT          99..175
FT                   /note="2"
SQ   SEQUENCE   189 AA;  21348 MW;  1FE1509E645E7980 CRC64;
     MSNVKLRIEN IVASVDLFTQ LNLERVIEMC PHSKYNPEEF PGIICRFDEP KVALLIFSSG
     KLVVTGAKSV EDIERAVNKL IQMLKKIGAK FSRAPQIDIQ NMVFSGDIGM EFNLDAVALS
     LPNCEYEPEQ FPGVIYRVKE PRAVILLFSS GKIVCSGAKS EHDAWEAVRK LLRELEKYDL
     IGEGEEEEW