ID   TBP_THEON               Reviewed;         192 AA.
AC   B6YXI6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=TATA-box-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=Box A-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=BAP {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA sequence-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE            Short=TBP {ECO:0000255|HAMAP-Rule:MF_00408};
DE   AltName: Full=TATA-box factor {ECO:0000255|HAMAP-Rule:MF_00408};
GN   Name=tbp {ECO:0000255|HAMAP-Rule:MF_00408}; OrderedLocusNames=TON_1309;
OS   Thermococcus onnurineus (strain NA1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=523850;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA1;
RX   PubMed=18790866; DOI=10.1128/jb.00746-08;
RA   Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H.,
RA   Cha S.-S., Kwon K.K., Kim H.-T., Park C.-J., Lee H.-W., Kim S.I., Chun J.,
RA   Colwell R.R., Kim S.-J., Lee J.-H.;
RT   "The complete genome sequence of Thermococcus onnurineus NA1 reveals a
RT   mixed heterotrophic and carboxydotrophic metabolism.";
RL   J. Bacteriol. 190:7491-7499(2008).
CC   -!- FUNCTION: General factor that plays a role in the activation of
CC       archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC       TATA box promoter element which lies close to the position of
CC       transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC   -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC       Rule:MF_00408}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000855; ACJ16799.1; -; Genomic_DNA.
DR   RefSeq; WP_012572271.1; NC_011529.1.
DR   AlphaFoldDB; B6YXI6; -.
DR   SMR; B6YXI6; -.
DR   STRING; 523850.TON_1309; -.
DR   PRIDE; B6YXI6; -.
DR   EnsemblBacteria; ACJ16799; ACJ16799; TON_1309.
DR   GeneID; 7018337; -.
DR   KEGG; ton:TON_1309; -.
DR   PATRIC; fig|523850.10.peg.1317; -.
DR   eggNOG; arCOG01764; Archaea.
DR   HOGENOM; CLU_060161_4_3_2; -.
DR   OMA; NCEYEPE; -.
DR   OrthoDB; 83880at2157; -.
DR   Proteomes; UP000002727; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   CDD; cd04518; TBP_archaea; 1.
DR   Gene3D; 3.30.310.10; -; 2.
DR   HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR   InterPro; IPR000814; TBP.
DR   InterPro; IPR033711; TBP_archaea.
DR   InterPro; IPR030491; TBP_CS.
DR   InterPro; IPR012295; TBP_dom_sf.
DR   PANTHER; PTHR10126; PTHR10126; 1.
DR   Pfam; PF00352; TBP; 2.
DR   PRINTS; PR00686; TIFACTORIID.
DR   PROSITE; PS00351; TFIID; 2.
PE   3: Inferred from homology;
KW   DNA-binding; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..192
FT                   /note="TATA-box-binding protein"
FT                   /id="PRO_1000196665"
FT   REPEAT          11..87
FT                   /note="1"
FT   REPEAT          102..178
FT                   /note="2"
SQ   SEQUENCE   192 AA;  21779 MW;  95A1D961DB58ADBE CRC64;
     MVDMSNVKLR IENIVASVDL FTQLNLEKVI EICPNSKYNP EEFPGIICRF EEPKVALLIF
     SSGKLVVTGA KSVEDIERAV NKLIQMLKRI GAKFQRAPQI DIQNMVFSGD IGMEFNLDAV
     ALSLPNCEYE PEQFPGVIYR VKEPRAVILL FSSGKIVCSG AKSEHDAWEA VRKLLRELEK
     YGLIEEDEEE EW