TBP_THEVO
ID TBP_THEVO Reviewed; 184 AA.
AC Q978J5;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2001, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=TATA-box-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=Box A-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=BAP {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA sequence-binding protein {ECO:0000255|HAMAP-Rule:MF_00408};
DE Short=TBP {ECO:0000255|HAMAP-Rule:MF_00408};
DE AltName: Full=TATA-box factor {ECO:0000255|HAMAP-Rule:MF_00408};
GN Name=tbp {ECO:0000255|HAMAP-Rule:MF_00408}; OrderedLocusNames=TV1420;
GN ORFNames=TVG1467237;
OS Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS 15438 / GSS1).
OC Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC Thermoplasmataceae; Thermoplasma.
OX NCBI_TaxID=273116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1;
RX PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT Thermoplasma volcanium.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC -!- FUNCTION: General factor that plays a role in the activation of
CC archaeal genes transcribed by RNA polymerase. Binds specifically to the
CC TATA box promoter element which lies close to the position of
CC transcription initiation. {ECO:0000255|HAMAP-Rule:MF_00408}.
CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000255|HAMAP-
CC Rule:MF_00408}.
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DR EMBL; BA000011; BAB60562.1; -; Genomic_DNA.
DR RefSeq; WP_010917652.1; NC_002689.2.
DR AlphaFoldDB; Q978J5; -.
DR SMR; Q978J5; -.
DR STRING; 273116.14325659; -.
DR EnsemblBacteria; BAB60562; BAB60562; BAB60562.
DR GeneID; 1442110; -.
DR KEGG; tvo:TVG1467237; -.
DR eggNOG; arCOG01764; Archaea.
DR HOGENOM; CLU_060161_4_3_2; -.
DR OMA; NCEYEPE; -.
DR OrthoDB; 83880at2157; -.
DR PhylomeDB; Q978J5; -.
DR Proteomes; UP000001017; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR CDD; cd04518; TBP_archaea; 1.
DR Gene3D; 3.30.310.10; -; 2.
DR HAMAP; MF_00408; TATA_bind_prot_arch; 1.
DR InterPro; IPR000814; TBP.
DR InterPro; IPR033711; TBP_archaea.
DR InterPro; IPR030491; TBP_CS.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR10126; PTHR10126; 1.
DR Pfam; PF00352; TBP; 2.
DR PRINTS; PR00686; TIFACTORIID.
DR PROSITE; PS00351; TFIID; 1.
PE 3: Inferred from homology;
KW DNA-binding; Repeat; Transcription; Transcription regulation.
FT CHAIN 1..184
FT /note="TATA-box-binding protein"
FT /id="PRO_0000154030"
FT REPEAT 9..85
FT /note="1"
FT REPEAT 100..178
FT /note="2"
SQ SEQUENCE 184 AA; 20518 MW; 178CB12561746F5F CRC64;
MSEREKITIE NIVASTSLAE HLDLSRIALA LDGSEYEPEQ FPGLIYRLQD PKTAVLIFRS
GKVNCTGAKN IEDVKRTIKI IIDKLKAANI EVYDDPDIIV QNIVAVYDLE SELNLTDIAM
SLGLENVEYE PEQFPGLVYR VEEPRVVLLL FGSGKVVCTG AKEESEIEQA VIKVKKELQK
VGLI