TBT1_ORYSJ
ID TBT1_ORYSJ Reviewed; 445 AA.
AC Q2R0K3;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Tryptamine benzoyltransferase 1 {ECO:0000305};
DE Short=OsTBT1 {ECO:0000303|PubMed:27354554};
DE EC=2.3.1.- {ECO:0000305};
GN Name=TBT1 {ECO:0000303|PubMed:27354554};
GN OrderedLocusNames=Os11g0642400 {ECO:0000312|EMBL:BAT15019.1},
GN LOC_Os11g42290 {ECO:0000312|EMBL:ABA95026.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION, AND BIOPHYSICOCHEMICAL PROPERTIES.
RX PubMed=27354554; DOI=10.1105/tpc.16.00265;
RA Peng M., Gao Y., Chen W., Wang W., Shen S., Shi J., Wang C., Zhang Y.,
RA Zou L., Wang S., Wan J., Liu X., Gong L., Luo J.;
RT "Evolutionarily distinct BAHD N-acyltransferases are responsible for
RT natural variation of aromatic amine conjugates in rice.";
RL Plant Cell 28:1533-1550(2016).
CC -!- FUNCTION: Hydroxycinnamoyl transferase that catalyzes the transfer of
CC an acyl from benzoyl-CoA to tryptamine, to produce benzoyl tryptamine.
CC Serotonin and tyramine serve as acyl acceptors in vitro. Can use p-
CC coumaroyl-CoA, and to a lesser extent caffeoyl-CoA, as acyl donors.
CC {ECO:0000269|PubMed:27354554}.
CC -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC Kinetic parameters:
CC KM=474.7 uM for benzoyl-CoA {ECO:0000269|PubMed:27354554};
CC KM=101.9 uM for p-coumaroyl-CoA {ECO:0000269|PubMed:27354554};
CC KM=979 uM for caffeoyl-CoA {ECO:0000269|PubMed:27354554};
CC KM=10.5 uM for tryptamine {ECO:0000269|PubMed:27354554};
CC KM=19.6 uM for serotonin {ECO:0000269|PubMed:27354554};
CC KM=15 uM for tyramine {ECO:0000269|PubMed:27354554};
CC -!- SIMILARITY: Belongs to the plant acyltransferase family. {ECO:0000305}.
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DR EMBL; DP000010; ABA95026.1; -; Genomic_DNA.
DR EMBL; AP008217; BAH95403.1; -; Genomic_DNA.
DR EMBL; AP014967; BAT15019.1; -; Genomic_DNA.
DR EMBL; AK241399; BAH01021.1; -; mRNA.
DR RefSeq; XP_015615935.1; XM_015760449.1.
DR AlphaFoldDB; Q2R0K3; -.
DR SMR; Q2R0K3; -.
DR STRING; 4530.OS11T0642400-01; -.
DR PaxDb; Q2R0K3; -.
DR PRIDE; Q2R0K3; -.
DR EnsemblPlants; Os11t0642400-01; Os11t0642400-01; Os11g0642400.
DR GeneID; 9271182; -.
DR Gramene; Os11t0642400-01; Os11t0642400-01; Os11g0642400.
DR KEGG; osa:9271182; -.
DR eggNOG; ENOG502QVP8; Eukaryota.
DR HOGENOM; CLU_014546_6_2_1; -.
DR InParanoid; Q2R0K3; -.
DR OMA; VTWARAV; -.
DR OrthoDB; 1130893at2759; -.
DR SABIO-RK; Q2R0K3; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR ExpressionAtlas; Q2R0K3; baseline and differential.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR GO; GO:0050734; F:hydroxycinnamoyltransferase activity; IDA:UniProtKB.
DR Gene3D; 3.30.559.10; -; 2.
DR InterPro; IPR023213; CAT-like_dom_sf.
PE 1: Evidence at protein level;
KW Acyltransferase; Reference proteome; Transferase.
FT CHAIN 1..445
FT /note="Tryptamine benzoyltransferase 1"
FT /id="PRO_0000437768"
FT ACT_SITE 150
FT /note="Proton acceptor"
FT /evidence="ECO:0000250|UniProtKB:Q8W1W9"
FT ACT_SITE 382
FT /note="Proton acceptor"
FT /evidence="ECO:0000250|UniProtKB:Q8W1W9"
SQ SEQUENCE 445 AA; 47715 MW; 865B3FA1DB81D8DD CRC64;
MEITSSAMLK TTTTPPHPLA GEKVPLSAFD RAAFDVFVPL VFAYRAPAPS SEAVKEGLRV
AVAAYPLVSG RIAVDGQGRR RRRRVLHVNN EGVLVLDATV EVDLDAVLAA NVATDLYPAL
PEHSFGAALL QVQLTRFGCG GLVVGLIGHH HVFDGHSMST FCATWARAVR DSEAFIVPSP
SLDRAITGVP RSPPAPVFDH RSIEFKVGNK SSDSSGAAAA AAVEKIANIG VRFTAKFVAE
LKARVGGRCS TFECVLAHAW KKITAARGLK PEEFTRVRVA VNCRRRANPP APADLFGNMV
LWAFPRLQVR RLLSSSYRDV VGAIRAAVAR VDAEYIQSFV DYVEVADARG EELAATAAEP
GETLCPDLEV DSWLGFRFHE MDLGTGPPAA VLSPDLPIEG LMILVPVGGD GGGVDLFVAL
ADDHAQAFEQ ICYSLEEHAM IHSHL
