ID   TBTA_ALTSM              Reviewed;         207 AA.
AC   P32820;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Putative tributyltin chloride resistance protein;
GN   Name=tbtA;
OS   Alteromonas sp. (strain M-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Alteromonas/Salinimonas group; Alteromonas.
OX   NCBI_TaxID=29457;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8343157; DOI=10.1006/bbrc.1993.1883;
RA   Fukagawa T., Suzuki S.;
RT   "Cloning of gene responsible for tributyltin chloride (TBTC1) resistance in
RT   TBTC1-resistant marine bacterium, Alteromonas sp. M-1.";
RL   Biochem. Biophys. Res. Commun. 194:733-740(1993).
RN   [2]
RP   SEQUENCE REVISION, AND SIMILARITY TO SLT.
RX   PubMed=8203016; DOI=10.1016/0968-0004(94)90201-1;
RA   Koonin E.V., Rudd K.E.;
RT   "A conserved domain in putative bacterial and bacteriophage
RT   transglycosylases.";
RL   Trends Biochem. Sci. 19:106-107(1994).
CC   -!- SIMILARITY: Belongs to the transglycosylase Slt family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=D16369; Type=Frameshift; Note=Extend the C-terminal part and restore the similarity to slt.; Evidence={ECO:0000305};
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DR   EMBL; D16369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P32820; -.
DR   SMR; P32820; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0008933; F:lytic transglycosylase activity; IEA:InterPro.
DR   GO; GO:0000270; P:peptidoglycan metabolic process; IEA:InterPro.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR000189; Transglyc_AS.
DR   InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR   Pfam; PF01464; SLT; 1.
DR   SUPFAM; SSF53955; SSF53955; 1.
DR   PROSITE; PS00922; TRANSGLYCOSYLASE; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..207
FT                   /note="Putative tributyltin chloride resistance protein"
FT                   /id="PRO_0000196565"
FT   REGION          37..122
FT                   /note="Slt-type domain"
FT   ACT_SITE        49
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10071"
SQ   SEQUENCE   207 AA;  23653 MW;  1DFA586F92558EEA CRC64;
     MYNNALHGIY LTQITWMKSA RAEPYLYYIV TEVEKRNLPI ELALMPLIES DFNASAYSHK
     HASGLWQLTP AIAKYFKVQI SPWYDGRQDV IDSTRAALNF MEYLHKRFDG DWYHAIAALN
     LGEGRVLRAI SNIKNKANPL IFQLKTAQTN QSVRAKRTSC GTIIKKPKNA FPAILNSPTI
     AVLPVDCAVI LDNRKQWQQL EIFKPMV