TBX11_CAEEL
ID TBX11_CAEEL Reviewed; 322 AA.
AC Q20257;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Putative T-box protein 11;
GN Name=tbx-11; ORFNames=F40H6.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
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DR EMBL; FO080364; CCD63187.1; -; Genomic_DNA.
DR PIR; E88473; E88473.
DR RefSeq; NP_498317.1; NM_065916.1.
DR AlphaFoldDB; Q20257; -.
DR SMR; Q20257; -.
DR BioGRID; 50343; 1.
DR IntAct; Q20257; 1.
DR STRING; 6239.F40H6.4; -.
DR PaxDb; Q20257; -.
DR EnsemblMetazoa; F40H6.4.1; F40H6.4.1; WBGene00006547.
DR GeneID; 185575; -.
DR KEGG; cel:CELE_F40H6.4; -.
DR UCSC; F40H6.4; c. elegans.
DR CTD; 185575; -.
DR WormBase; F40H6.4; CE01281; WBGene00006547; tbx-11.
DR eggNOG; KOG3585; Eukaryota.
DR HOGENOM; CLU_032588_1_0_1; -.
DR InParanoid; Q20257; -.
DR OMA; LLTQHRY; -.
DR OrthoDB; 1545766at2759; -.
DR PhylomeDB; Q20257; -.
DR Reactome; R-CEL-2032785; YAP1- and WWTR1 (TAZ)-stimulated gene expression.
DR SignaLink; Q20257; -.
DR PRO; PR:Q20257; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00006547; Expressed in embryo and 4 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0001708; P:cell fate specification; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00182; TBOX; 1.
DR Gene3D; 2.60.40.820; -; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; PTHR11267; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; SSF49417; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..322
FT /note="Putative T-box protein 11"
FT /id="PRO_0000184473"
FT DNA_BIND 16..185
FT /note="T-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00201"
FT REGION 171..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 36512 MW; 7984F0203F5F741F CRC64;
MDQPISVTLS STTDPLWRSC HEYDNEMVIT VNGRRIFPTL EYTVTGLDTF KLYSMCMHLD
LVDDKKLRFT GGQWAESVST EKKDPPRKVW HHNGSQTGKD WMLRNVSFDQ IRITNRKSKE
DGNASYVHLL TQHRYIPVLT IYEGDQLVHT ARIPHSQFIS VTAYHKGELN TLKTNNNPYS
TGSRKDRRRE RQSPVYSEGT SSEKSISPPP AKKIKDMAPA LPDYSVISKP NLLQSLIFPM
IAEQPSTSQS PPAPPVFPFN PDLQMQMLQP FMLPQFGFPC GFPSINPFMN PFLTPFTSMF
PTPTVSPDGE GVKLEPEAFV EV
