TBX32_CAEEL
ID TBX32_CAEEL Reviewed; 441 AA.
AC O61764;
DT 16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 3.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Putative T-box protein 32;
GN Name=tbx-32; ORFNames=ZK380.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FO081544; CCD72316.1; -; Genomic_DNA.
DR PIR; E89467; E89467.
DR PIR; T33067; T33067.
DR RefSeq; NP_508304.2; NM_075903.3.
DR AlphaFoldDB; O61764; -.
DR SMR; O61764; -.
DR STRING; 6239.ZK380.1; -.
DR PaxDb; O61764; -.
DR EnsemblMetazoa; ZK380.1.1; ZK380.1.1; WBGene00006551.
DR GeneID; 191303; -.
DR KEGG; cel:CELE_ZK380.1; -.
DR UCSC; ZK380.1; c. elegans.
DR CTD; 191303; -.
DR WormBase; ZK380.1; CE41092; WBGene00006551; tbx-32.
DR eggNOG; KOG3585; Eukaryota.
DR GeneTree; ENSGT00970000197570; -.
DR HOGENOM; CLU_621486_0_0_1; -.
DR PhylomeDB; O61764; -.
DR Reactome; R-CEL-2032785; YAP1- and WWTR1 (TAZ)-stimulated gene expression.
DR PRO; PR:O61764; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00006551; Expressed in embryo and 1 other tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0001708; P:cell fate specification; IBA:GO_Central.
DR GO; GO:0003007; P:heart morphogenesis; IBA:GO_Central.
DR GO; GO:0001707; P:mesoderm formation; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 2.60.40.820; -; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; PTHR11267; 1.
DR Pfam; PF00907; T-box; 1.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; SSF49417; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..441
FT /note="Putative T-box protein 32"
FT /id="PRO_0000184477"
FT DNA_BIND 18..199
FT /note="T-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00201"
FT REGION 268..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 441 AA; 50288 MW; 2877173D36CD7319 CRC64;
MTSQYSNYSC PLNNIQVNVI GSSRTSDDHF LEQMLTKRKK TNISQDLHYT LLGLNPRDLY
QISIKLARID EKKYKFNGNF NGGDYYPHKN SEIPMEDTEE IVHLDGYQTG ARWMKTGVYF
PKIGISKEQP DKERCLLLES LHAYVPVLRF TTSSGISLEV TVWSQKFVTT MTSSNRSVKR
REKRKLEETT GPSAKKTPEV IEFTQEAVVP EVYNAQQVYQ MQNDTMISSD SKFCSPLAFQ
QDFTEEFGTI SQLDAYVNVN VQSCSSSSLS SPAALQQDST VSSDNDFDDK NSEEFDAVFE
YIDQQFSNHD QNPMDQQSKS IDLNQTTWTS QSINNQSYLS TASSPAALNQ DSFASEKSSI
VRDKKNDENC LDEFDRVFNE LDQQFTPTEN QLQDLSNCTT WNQEPINNSI QSNQLNNNIA
PALEENVEDD NAIFEHFFIC N