TBX33_CAEEL
ID TBX33_CAEEL Reviewed; 420 AA.
AC O45291;
DT 16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 2.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Putative T-box protein 33;
GN Name=tbx-33; ORFNames=Y66A7A.8;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
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DR EMBL; AL590342; CAC35862.2; -; Genomic_DNA.
DR EMBL; AL032627; CAC35862.2; JOINED; Genomic_DNA.
DR PIR; T26809; T26809.
DR RefSeq; NP_499506.2; NM_067105.3.
DR AlphaFoldDB; O45291; -.
DR SMR; O45291; -.
DR BioGRID; 55077; 4.
DR IntAct; O45291; 4.
DR STRING; 6239.Y66A7A.8; -.
DR PaxDb; O45291; -.
DR EnsemblMetazoa; Y66A7A.8.1; Y66A7A.8.1; WBGene00006552.
DR GeneID; 190493; -.
DR KEGG; cel:CELE_Y66A7A.8; -.
DR UCSC; Y66A7A.8; c. elegans.
DR CTD; 190493; -.
DR WormBase; Y66A7A.8; CE43263; WBGene00006552; tbx-33.
DR eggNOG; KOG3585; Eukaryota.
DR HOGENOM; CLU_654234_0_0_1; -.
DR InParanoid; O45291; -.
DR OMA; EVSNECK; -.
DR OrthoDB; 1838820at2759; -.
DR PhylomeDB; O45291; -.
DR Reactome; R-CEL-2032785; YAP1- and WWTR1 (TAZ)-stimulated gene expression.
DR PRO; PR:O45291; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00006552; Expressed in embryo and 2 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0001708; P:cell fate specification; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 2.60.40.820; -; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; PTHR11267; 3.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; SSF49417; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..420
FT /note="Putative T-box protein 33"
FT /id="PRO_0000184478"
FT DNA_BIND 93..291
FT /note="T-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00201"
FT REGION 395..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 420 AA; 48052 MW; 2E8DBDF659009B72 CRC64;
MNYQNEQNAY QMQNQENVPP MSYGYPMPTP EQFQKMSYGQ NFQAPWDMQQ QIQMFQQYHQ
NFQGGYSDPF TYQNQYAHQP KIVTVTLQDP QDLWKELHYL SNEQNVLNNG RKIFPALNYK
VEHLNPESNY KVEILLRRMV PYQIQYSNGS WSRKNVQSKK TIAMKTEKVF VGEFTGQDIM
RTGLDLSDVK VFNIGSDNKK KVTPYEEMSD AEKREYDTQY SKKKTSMLEV SNECKYIPVL
IINEILPNQE LRLVGEFENE ITQFATVSSY KNHIVKALRT AANPTSRGDA KQEAVQVGKQ
WRSSNKSLLE SLRPSMICTS VSTTAPSTNF HAPLQYPGTS SPSSNFAPMT PSTSFDSAYS
SFNVTSSTPE QMCYNPIPSM STDYSFCSFD SATSSPPLQP TATSPEASQN QIKLEMNQYM
