TBX37_CAEEL
ID TBX37_CAEEL Reviewed; 313 AA.
AC Q9U2C9;
DT 16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Putative T-box protein 37;
GN Name=tbx-37; ORFNames=Y47D3A.12;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
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DR EMBL; AL117202; CAB57892.2; -; Genomic_DNA.
DR PIR; T31544; T31544.
DR RefSeq; NP_499444.2; NM_067043.3.
DR AlphaFoldDB; Q9U2C9; -.
DR SMR; Q9U2C9; -.
DR BioGRID; 54587; 4.
DR IntAct; Q9U2C9; 4.
DR STRING; 6239.Y47D3A.12; -.
DR PaxDb; Q9U2C9; -.
DR EnsemblMetazoa; Y47D3A.12.1; Y47D3A.12.1; WBGene00006556.
DR GeneID; 189977; -.
DR KEGG; cel:CELE_Y47D3A.12; -.
DR UCSC; Y47D3A.12; c. elegans.
DR CTD; 189977; -.
DR WormBase; Y47D3A.12; CE44340; WBGene00006556; tbx-37.
DR eggNOG; KOG3585; Eukaryota.
DR GeneTree; ENSGT00970000196046; -.
DR HOGENOM; CLU_032588_0_0_1; -.
DR InParanoid; Q9U2C9; -.
DR OMA; LYTVHIH; -.
DR OrthoDB; 9090at6231; -.
DR PhylomeDB; Q9U2C9; -.
DR Reactome; R-CEL-2032785; YAP1- and WWTR1 (TAZ)-stimulated gene expression.
DR PRO; PR:Q9U2C9; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00006556; Expressed in embryo and 1 other tissue.
DR GO; GO:0005634; C:nucleus; IDA:WormBase.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0001708; P:cell fate specification; IBA:GO_Central.
DR GO; GO:0060465; P:pharynx development; IGI:WormBase.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00182; TBOX; 1.
DR Gene3D; 2.60.40.820; -; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; PTHR11267; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; SSF49417; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..313
FT /note="Putative T-box protein 37"
FT /id="PRO_0000184482"
FT DNA_BIND 19..195
FT /note="T-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00201"
FT REGION 193..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 36140 MW; 94E085C8152982E3 CRC64;
MYSCTSPSGI EVSLNKPEIW EKFYPKTEMI VTRKRGRVIF PHLDYNVKGL DPDSLYSIYI
HLERVDGIKY KFDAGEWKEA GKGDPILPIQ YKEHPRGKRT GTEWMSEPVS FAHLKITNDP
ENKDQKLILA QSLHKYIPVL HIKQLDPYKG TFQMDFHGVE FRLEATQFIV VTAYQNEELT
KLKVHHNKFA SGFRSNGKRR LSSESENSEN SPPKRSASAI SSLTPPAISP PMDYTQQNPY
FFNQNFFSTP QSHQPQFAAH SANAQNYNNF GAQNGAQFDW NVYYQRQWYW QQQMMMSGGI
GQPQMLNNGF PNL
