TBX38_CAEEL
ID TBX38_CAEEL Reviewed; 303 AA.
AC Q9XVD5;
DT 16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Putative T-box protein 38;
GN Name=tbx-38; ORFNames=C24H11.3;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- INTERACTION:
CC Q9XVD5; Q10666: pop-1; NbExp=3; IntAct=EBI-2413404, EBI-317870;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
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DR EMBL; Z81475; CAB03909.1; -; Genomic_DNA.
DR PIR; T19424; T19424.
DR RefSeq; NP_499526.1; NM_067125.1.
DR AlphaFoldDB; Q9XVD5; -.
DR SMR; Q9XVD5; -.
DR BioGRID; 47701; 8.
DR IntAct; Q9XVD5; 8.
DR STRING; 6239.C24H11.3; -.
DR PaxDb; Q9XVD5; -.
DR EnsemblMetazoa; C24H11.3.1; C24H11.3.1; WBGene00006557.
DR GeneID; 182861; -.
DR KEGG; cel:CELE_C24H11.3; -.
DR UCSC; C24H11.3; c. elegans.
DR CTD; 182861; -.
DR WormBase; C24H11.3; CE18526; WBGene00006557; tbx-38.
DR eggNOG; KOG3585; Eukaryota.
DR GeneTree; ENSGT00970000196046; -.
DR HOGENOM; CLU_032588_0_0_1; -.
DR InParanoid; Q9XVD5; -.
DR OMA; EFMVVTA; -.
DR OrthoDB; 9090at6231; -.
DR PhylomeDB; Q9XVD5; -.
DR Reactome; R-CEL-2032785; YAP1- and WWTR1 (TAZ)-stimulated gene expression.
DR SignaLink; Q9XVD5; -.
DR PRO; PR:Q9XVD5; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00006557; Expressed in embryo and 2 other tissues.
DR GO; GO:0005634; C:nucleus; IDA:WormBase.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0001708; P:cell fate specification; IBA:GO_Central.
DR GO; GO:0060465; P:pharynx development; IGI:WormBase.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00182; TBOX; 1.
DR Gene3D; 2.60.40.820; -; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; PTHR11267; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; SSF49417; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..303
FT /note="Putative T-box protein 38"
FT /id="PRO_0000184483"
FT DNA_BIND 14..195
FT /note="T-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00201"
FT REGION 193..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 303 AA; 35530 MW; 4539EDC83FCAFC60 CRC64;
MYSCTSPSGI KVSLSTPEIW EEFYPKTEMI VTRNRGRVIF PHLDYIIKGL DPGSLYSIYI
HLERVDGIKY KFDAGEWKEF AKGDPILPIQ YKEHPRGKRT GAEWMSEPVS FAHIKITNNP
EIKDQKVILV QSMHKHIPVV TVKQVRHYKT GYQEDFSGEQ FRLEATEFMV VTAYQNEILK
NLKVHHNKFA SGFRSNGKRR LSSDSENSEN SPPKRSKLVT PPTISPQIDL PQQTPYYFNQ
NFVAPQNYQP QFASAQNYNF EVQNNAQLAW NMYYQKQYEF WWQQQQMMMP GQPQELKNEF
QSL
