TBX39_CAEEL
ID TBX39_CAEEL Reviewed; 396 AA.
AC Q9NA56;
DT 16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Putative T-box protein 39;
GN Name=tbx-39; ORFNames=Y73F8A.16;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- INTERACTION:
CC Q9NA56; Q9XWH5: CELE_Y57A10B.6; NbExp=4; IntAct=EBI-2412056, EBI-331440;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
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DR EMBL; AL132862; CAB60541.1; -; Genomic_DNA.
DR RefSeq; NP_502851.1; NM_070450.1.
DR AlphaFoldDB; Q9NA56; -.
DR SMR; Q9NA56; -.
DR BioGRID; 55257; 18.
DR IntAct; Q9NA56; 18.
DR STRING; 6239.Y73F8A.16; -.
DR PaxDb; Q9NA56; -.
DR EnsemblMetazoa; Y73F8A.16.1; Y73F8A.16.1; WBGene00006558.
DR GeneID; 190678; -.
DR KEGG; cel:CELE_Y73F8A.16; -.
DR UCSC; Y73F8A.16; c. elegans.
DR CTD; 190678; -.
DR WormBase; Y73F8A.16; CE22985; WBGene00006558; tbx-39.
DR eggNOG; KOG3585; Eukaryota.
DR GeneTree; ENSGT00970000196896; -.
DR HOGENOM; CLU_728115_0_0_1; -.
DR InParanoid; Q9NA56; -.
DR OMA; HALNTEM; -.
DR OrthoDB; 1809882at2759; -.
DR PhylomeDB; Q9NA56; -.
DR Reactome; R-CEL-2032785; YAP1- and WWTR1 (TAZ)-stimulated gene expression.
DR SignaLink; Q9NA56; -.
DR PRO; PR:Q9NA56; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00006558; Expressed in embryo and 1 other tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0001708; P:cell fate specification; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 2.60.40.820; -; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; PTHR11267; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; SSF49417; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..396
FT /note="Putative T-box protein 39"
FT /id="PRO_0000184484"
FT DNA_BIND 11..192
FT /note="T-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00201"
FT REGION 185..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..215
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 396 AA; 46381 MW; DDF75C664CF4481B CRC64;
MFSQAQFNVT MAEEDRWKQW YPNMEMIVNN KGPKLIFPEL NFNITGLEEK SRYVVLLSIE
KYDNIRYGYR NGKWGPSKVR HATKKEQEIK YFLHPDGTKL GKELMKETIK FDTVRITNHK
KFMDKDNVFF VETMHKYVPV LTVKNITNVE SANHSMRMEV AQFFPVTVYN QESIGNWKSK
FHKNSTYGNR LDGGNKRKNT DSSEERTSKR SKNETEIAVS DILQVASQSE NYNESTNSGR
LQNEISSSIH QFPSTSYQNQ YPHAYPTVNT PPIYVQQFTA LFDEIHNQFD PKTKQNRVAK
NVQYLSSVPQ FAINQKENIH QNAPDYPVSQ FPNQYPYGSY PYYYPYFQSS QQFPHLNYSM
NNSIYSDSSF QSSFSAENSY FDENGNPIHY PYYSSN
