ID   TBX40_CAEEL             Reviewed;         380 AA.
AC   Q9NA55;
DT   16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Putative T-box protein 40;
GN   Name=tbx-40; ORFNames=Y73F8A.17;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
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DR   EMBL; AL132862; CAB60542.1; -; Genomic_DNA.
DR   RefSeq; NP_502852.1; NM_070451.1.
DR   AlphaFoldDB; Q9NA55; -.
DR   SMR; Q9NA55; -.
DR   STRING; 6239.Y73F8A.17; -.
DR   EPD; Q9NA55; -.
DR   PaxDb; Q9NA55; -.
DR   EnsemblMetazoa; Y73F8A.17.1; Y73F8A.17.1; WBGene00006559.
DR   GeneID; 190679; -.
DR   KEGG; cel:CELE_Y73F8A.17; -.
DR   UCSC; Y73F8A.17; c. elegans.
DR   CTD; 190679; -.
DR   WormBase; Y73F8A.17; CE22986; WBGene00006559; tbx-40.
DR   eggNOG; KOG3585; Eukaryota.
DR   GeneTree; ENSGT00940000170863; -.
DR   HOGENOM; CLU_728115_0_0_1; -.
DR   InParanoid; Q9NA55; -.
DR   OMA; DNIRYGF; -.
DR   OrthoDB; 1809882at2759; -.
DR   PhylomeDB; Q9NA55; -.
DR   Reactome; R-CEL-2032785; YAP1- and WWTR1 (TAZ)-stimulated gene expression.
DR   PRO; PR:Q9NA55; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00006559; Expressed in embryo and 1 other tissue.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0001708; P:cell fate specification; IBA:GO_Central.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 2.60.40.820; -; 1.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd.
DR   InterPro; IPR046360; T-box_DNA-bd.
DR   InterPro; IPR036960; T-box_sf.
DR   InterPro; IPR001699; TF_T-box.
DR   InterPro; IPR018186; TF_T-box_CS.
DR   PANTHER; PTHR11267; PTHR11267; 1.
DR   Pfam; PF00907; T-box; 1.
DR   PRINTS; PR00937; TBOX.
DR   SMART; SM00425; TBOX; 1.
DR   SUPFAM; SSF49417; SSF49417; 1.
DR   PROSITE; PS01264; TBOX_2; 1.
DR   PROSITE; PS50252; TBOX_3; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..380
FT                   /note="Putative T-box protein 40"
FT                   /id="PRO_0000184485"
FT   DNA_BIND        11..192
FT                   /note="T-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00201"
FT   REGION          188..215
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   380 AA;  44275 MW;  ECAD305550247406 CRC64;
     MIQQAQFNVQ MAEEDRWLTQ YPNMEMIVNN KGPKPIFPEL NFNITGLEEK SRYVVLLSIQ
     KFDNIRYGFK NGKWGPSKVR HATKKEQEIK YFLHPDGTKL GEELMKETIK FDTVRITNHK
     KFMDKDNVFF VETMHKYVPV LTVKNITNVE SANHSMRMEV AQFFPVTVYN QESIGNWKSK
     FHKNATFENR LDGGNKRKNT NSREEPSSKR SKNETEIAVL DILQVASQSE NYNESTNSGR
     LQNEISSSIH QFPSTSYQNQ YPHAYPTVNT PPIYAQQFPA PFDEKQNQFY PKTDENLAPN
     CAQDASSLPN FAMNQKASFA NQYPYHPYYH QYSQLDHGSP YQYMNNSINS DSSFQSSFST
     ENSYFDDNGN PIHYPYYPYK