TCAL1_GORGO
ID TCAL1_GORGO Reviewed; 159 AA.
AC A1YEW9;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Transcription elongation factor A protein-like 1 {ECO:0000250|UniProtKB:Q15170};
DE Short=TCEA-like protein 1;
DE AltName: Full=Transcription elongation factor S-II protein-like 1;
GN Name=TCEAL1 {ECO:0000250|UniProtKB:Q15170};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Nickel G.C., Tefft D.L., Trevarthen K., Funt J., Adams M.D.;
RT "Positive selection in transcription factor genes on the human lineage.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation. Modulates
CC various viral and cellular promoters in a promoter context-dependent
CC manner. Does not bind DNA directly (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TFS-II family. TFA subfamily. {ECO:0000305}.
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DR EMBL; DQ976479; ABM46687.1; -; Genomic_DNA.
DR RefSeq; XP_004064646.1; XM_004064598.2.
DR RefSeq; XP_004064647.1; XM_004064599.2.
DR RefSeq; XP_018875292.1; XM_019019747.1.
DR RefSeq; XP_018875293.1; XM_019019748.1.
DR AlphaFoldDB; A1YEW9; -.
DR STRING; 9593.ENSGGOP00000019189; -.
DR Ensembl; ENSGGOT00000012386; ENSGGOP00000012041; ENSGGOG00000012344.
DR GeneID; 101132699; -.
DR KEGG; ggo:101132699; -.
DR CTD; 9338; -.
DR eggNOG; ENOG502TCYF; Eukaryota.
DR GeneTree; ENSGT00950000183164; -.
DR HOGENOM; CLU_140430_0_0_1; -.
DR InParanoid; A1YEW9; -.
DR OMA; RPPQECL; -.
DR OrthoDB; 1545661at2759; -.
DR Proteomes; UP000001519; Chromosome X.
DR Bgee; ENSGGOG00000012344; Expressed in prefrontal cortex and 5 other tissues.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0050699; F:WW domain binding; IBA:GO_Central.
DR InterPro; IPR010370; TCEAL1.
DR InterPro; IPR021156; TF_A-like/BEX.
DR PANTHER; PTHR14754:SF12; PTHR14754:SF12; 1.
DR Pfam; PF04538; BEX; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..159
FT /note="Transcription elongation factor A protein-like 1"
FT /id="PRO_0000285498"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 159 AA; 18613 MW; 73B5224005A4A466 CRC64;
MDKPRKENEE EPQSAPKTDE ERPPVEHSPE KQSPEEQSSE EQSSEEEFFP EELLPELLPE
MLLSEERPPQ EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFKGDIHGR
NLSNEEMIQA ADELEEMKRV RNKLMIMHWK AKRSRPYPI