TCAL1_MACNE
ID TCAL1_MACNE Reviewed; 159 AA.
AC A2T6K9;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Transcription elongation factor A protein-like 1 {ECO:0000250|UniProtKB:Q15170};
DE Short=TCEA-like protein 1;
DE AltName: Full=Transcription elongation factor S-II protein-like 1;
GN Name=TCEAL1 {ECO:0000250|UniProtKB:Q15170};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Nickel G.C., Tefft D.L., Trevarthen K., Funt J., Adams M.D.;
RT "Positive selection in transcription factor genes on the human lineage.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation. Modulates
CC various viral and cellular promoters in a promoter context-dependent
CC manner. Does not bind DNA directly (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TFS-II family. TFA subfamily. {ECO:0000305}.
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DR EMBL; DQ977101; ABM88057.1; -; Genomic_DNA.
DR RefSeq; XP_011770891.1; XM_011772589.1.
DR RefSeq; XP_011770892.1; XM_011772590.1.
DR RefSeq; XP_011770893.1; XM_011772591.1.
DR RefSeq; XP_011770894.1; XM_011772592.1.
DR RefSeq; XP_011770895.1; XM_011772593.1.
DR RefSeq; XP_011770896.1; XM_011772594.1.
DR AlphaFoldDB; A2T6K9; -.
DR STRING; 9545.ENSMNEP00000028355; -.
DR Ensembl; ENSMNET00000052687; ENSMNEP00000028355; ENSMNEG00000037619.
DR GeneID; 105499788; -.
DR CTD; 9338; -.
DR GeneTree; ENSGT00950000183164; -.
DR OMA; RPPQECL; -.
DR OrthoDB; 1545661at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000037619; Expressed in pituitary gland and 12 other tissues.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR InterPro; IPR010370; TCEAL1.
DR InterPro; IPR021156; TF_A-like/BEX.
DR PANTHER; PTHR14754:SF12; PTHR14754:SF12; 1.
DR Pfam; PF04538; BEX; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..159
FT /note="Transcription elongation factor A protein-like 1"
FT /id="PRO_0000285501"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 159 AA; 18657 MW; FB45225045B62B46 CRC64;
MDKPRKENEE EPQSAPKTDE ERPPVEHSPE KQSLEEQSSE EQSSEEEFFP EELLPELLPE
MLLSEERPPQ EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFRGDIHGR
NLSNEEMIQA ADELEEMKRV RNKLMIMHWK AKRSRPYPI