TCAL1_MOUSE
ID TCAL1_MOUSE Reviewed; 165 AA.
AC Q921P9;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Transcription elongation factor A protein-like 1 {ECO:0000305};
DE Short=TCEA-like protein 1;
DE AltName: Full=Transcription elongation factor S-II protein-like 1;
GN Name=Tceal1 {ECO:0000312|MGI:MGI:2385317};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Czech II, and FVB/N-3; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation. Modulates
CC various viral and cellular promoters in a promoter context-dependent
CC manner. Does not bind DNA directly (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TFS-II family. TFA subfamily. {ECO:0000305}.
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DR EMBL; BC011290; AAH11290.1; -; mRNA.
DR EMBL; BC083157; AAH83157.1; -; mRNA.
DR CCDS; CCDS30421.1; -.
DR RefSeq; NP_666348.1; NM_146236.1.
DR RefSeq; XP_006528579.1; XM_006528516.3.
DR RefSeq; XP_006528580.1; XM_006528517.2.
DR AlphaFoldDB; Q921P9; -.
DR BioGRID; 231835; 1.
DR STRING; 10090.ENSMUSP00000061875; -.
DR iPTMnet; Q921P9; -.
DR PhosphoSitePlus; Q921P9; -.
DR MaxQB; Q921P9; -.
DR PaxDb; Q921P9; -.
DR PRIDE; Q921P9; -.
DR ProteomicsDB; 263086; -.
DR Antibodypedia; 29090; 368 antibodies from 30 providers.
DR DNASU; 237052; -.
DR Ensembl; ENSMUST00000055104; ENSMUSP00000061875; ENSMUSG00000049536.
DR GeneID; 237052; -.
DR KEGG; mmu:237052; -.
DR UCSC; uc009uit.1; mouse.
DR CTD; 9338; -.
DR MGI; MGI:2385317; Tceal1.
DR VEuPathDB; HostDB:ENSMUSG00000049536; -.
DR eggNOG; ENOG502TCYF; Eukaryota.
DR GeneTree; ENSGT00950000183164; -.
DR HOGENOM; CLU_140430_0_0_1; -.
DR InParanoid; Q921P9; -.
DR OMA; RPPQECL; -.
DR OrthoDB; 1545661at2759; -.
DR PhylomeDB; Q921P9; -.
DR TreeFam; TF336871; -.
DR BioGRID-ORCS; 237052; 0 hits in 73 CRISPR screens.
DR PRO; PR:Q921P9; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q921P9; protein.
DR Bgee; ENSMUSG00000049536; Expressed in dorsomedial nucleus of hypothalamus and 228 other tissues.
DR Genevisible; Q921P9; MM.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR GO; GO:0005634; C:nucleus; ISO:MGI.
DR GO; GO:0050699; F:WW domain binding; IBA:GO_Central.
DR InterPro; IPR010370; TCEAL1.
DR InterPro; IPR021156; TF_A-like/BEX.
DR PANTHER; PTHR14754:SF12; PTHR14754:SF12; 1.
DR Pfam; PF04538; BEX; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..165
FT /note="Transcription elongation factor A protein-like 1"
FT /id="PRO_0000239204"
FT REGION 1..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..59
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 165 AA; 19312 MW; 00C754D9FF2740BA CRC64;
MENTRSENEE QPESTLKIDE EQPAVEQSPE NQCSEEDQSS EDLSSEEQSS EEEFFPEELL
PELLPEMLLS EDRPPQECLS QKNQFEDRIP MEQPPCGVGK HKLEEGSFKE RLARIRPQFI
GDIHGRNLSN EEMIQAADEL EEMKRVRNKL MIMHWKAKRS RPYPI
