TCAL8_RAT
ID TCAL8_RAT Reviewed; 117 AA.
AC Q6I7R5;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Transcription elongation factor A protein-like 8;
DE Short=TCEA-like protein 8;
DE AltName: Full=Transcription elongation factor S-II protein-like 8;
DE AltName: Full=Up-regulated in nephrectomized rat kidney #1;
GN Name=Tceal8; ORFNames=UR-NR#1;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=Wistar; TISSUE=Kidney;
RX PubMed=15200410; DOI=10.1111/j.1523-1755.2004.00704.x;
RA Horiba N., Masuda S., Takeuchi A., Saito H., Okuda M., Inui K.;
RT "Gene expression variance based on random sequencing in rat remnant
RT kidney.";
RL Kidney Int. 66:29-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Highly expressed in kidney. Moderately expressed in
CC heart and lung. Low expression in brain and liver. Expression is up-
CC regulated in nephrectomized kidney. {ECO:0000269|PubMed:15200410}.
CC -!- SIMILARITY: Belongs to the TFS-II family. TFA subfamily. {ECO:0000305}.
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DR EMBL; AB108667; BAD23892.1; -; mRNA.
DR EMBL; BC086418; AAH86418.1; -; mRNA.
DR RefSeq; NP_001014297.1; NM_001014275.1.
DR AlphaFoldDB; Q6I7R5; -.
DR SMR; Q6I7R5; -.
DR STRING; 10116.ENSRNOP00000053943; -.
DR PaxDb; Q6I7R5; -.
DR PRIDE; Q6I7R5; -.
DR Ensembl; ENSRNOT00000017138; ENSRNOP00000053943; ENSRNOG00000028585.
DR Ensembl; ENSRNOT00000097834; ENSRNOP00000080501; ENSRNOG00000028585.
DR Ensembl; ENSRNOT00000102117; ENSRNOP00000096711; ENSRNOG00000028585.
DR Ensembl; ENSRNOT00000118719; ENSRNOP00000086262; ENSRNOG00000028585.
DR GeneID; 367909; -.
DR KEGG; rno:367909; -.
DR UCSC; RGD:1359631; rat.
DR CTD; 90843; -.
DR RGD; 1359631; Tceal8.
DR eggNOG; ENOG502R12B; Eukaryota.
DR GeneTree; ENSGT00950000183164; -.
DR HOGENOM; CLU_181913_0_0_1; -.
DR InParanoid; Q6I7R5; -.
DR OMA; HPYPVCF; -.
DR OrthoDB; 1497581at2759; -.
DR PhylomeDB; Q6I7R5; -.
DR PRO; PR:Q6I7R5; -.
DR Proteomes; UP000002494; Chromosome X.
DR Bgee; ENSRNOG00000028585; Expressed in ovary and 20 other tissues.
DR Genevisible; Q6I7R5; RN.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0050699; F:WW domain binding; IBA:GO_Central.
DR InterPro; IPR021156; TF_A-like/BEX.
DR Pfam; PF04538; BEX; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..117
FT /note="Transcription elongation factor A protein-like 8"
FT /id="PRO_0000239218"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 73..100
FT /evidence="ECO:0000255"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 117 AA; 13447 MW; AC9F19DE6C7CBD9F CRC64;
MQKSCDENEG TPQNTPKADE GHPSEDPPQQ AGENLQASGE NVREETDGSL RGEPAEPSPE
PKEDTPARHL NPEEVIRGVD ELERLREEIR RVRNKFVLMH WKQRHSRSRP YPVCFRP
