TCAL9_MOUSE
ID TCAL9_MOUSE Reviewed; 104 AA.
AC Q9DD24; A3KG99; O08549;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Transcription elongation factor A protein-like 9 {ECO:0000250|UniProtKB:Q9UHQ7};
DE Short=TCEA-like protein 9;
DE AltName: Full=Schlafen 8-interacting protein {ECO:0000303|Ref.2};
DE AltName: Full=Transcription elongation factor S-II protein-like 9;
DE AltName: Full=WW domain-binding protein 5;
DE Short=WBP-5;
GN Name=Tceal9; Synonyms=Wbp5;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Limb;
RX PubMed=9171351; DOI=10.1093/emboj/16.9.2376;
RA Bedford M.T., Chan D.C., Leder P.;
RT "FBP WW domains and the Abl SH3 domain bind to a specific class of proline-
RT rich ligands.";
RL EMBO J. 16:2376-2383(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=C57BL/6J; TISSUE=Macrophage;
RA Kaiser F., Kaufmann S.H.E., Zerrahn J.;
RT "Schlafen 8 (Slfn8) implicated in control of lymphoid differentiation and
RT growth interacts with a new transcription elongation factor II-S like
RT (TCEAL)-related protein.";
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Kidney;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May be involved in transcriptional regulation. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TFS-II family. TFA subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC53191.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};
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DR EMBL; U92454; AAC53191.1; ALT_SEQ; mRNA.
DR EMBL; AY459189; AAS16484.1; -; mRNA.
DR EMBL; AK002214; BAB21940.1; -; mRNA.
DR EMBL; AL671493; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC007478; AAH07478.1; -; mRNA.
DR CCDS; CCDS30418.1; -.
DR RefSeq; NP_035842.1; NM_011712.2.
DR AlphaFoldDB; Q9DD24; -.
DR STRING; 10090.ENSMUSP00000047474; -.
DR iPTMnet; Q9DD24; -.
DR PhosphoSitePlus; Q9DD24; -.
DR MaxQB; Q9DD24; -.
DR PaxDb; Q9DD24; -.
DR PRIDE; Q9DD24; -.
DR ProteomicsDB; 263260; -.
DR Antibodypedia; 1302; 61 antibodies from 14 providers.
DR DNASU; 22381; -.
DR Ensembl; ENSMUST00000048687; ENSMUSP00000047474; ENSMUSG00000042712.
DR Ensembl; ENSMUST00000113115; ENSMUSP00000108740; ENSMUSG00000042712.
DR GeneID; 22381; -.
DR KEGG; mmu:22381; -.
DR UCSC; uc009uij.1; mouse.
DR CTD; 51186; -.
DR MGI; MGI:109567; Tceal9.
DR VEuPathDB; HostDB:ENSMUSG00000042712; -.
DR eggNOG; ENOG502R6G6; Eukaryota.
DR GeneTree; ENSGT00950000183164; -.
DR HOGENOM; CLU_181913_0_0_1; -.
DR InParanoid; Q9DD24; -.
DR OMA; KLVVMRW; -.
DR OrthoDB; 1594253at2759; -.
DR PhylomeDB; Q9DD24; -.
DR BioGRID-ORCS; 22381; 3 hits in 72 CRISPR screens.
DR ChiTaRS; Tceal9; mouse.
DR PRO; PR:Q9DD24; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q9DD24; protein.
DR Bgee; ENSMUSG00000042712; Expressed in urogenital fold and 261 other tissues.
DR Genevisible; Q9DD24; MM.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0050699; F:WW domain binding; IBA:GO_Central.
DR InterPro; IPR021156; TF_A-like/BEX.
DR Pfam; PF04538; BEX; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..104
FT /note="Transcription elongation factor A protein-like 9"
FT /id="PRO_0000274047"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 104 AA; 12664 MW; 24512AC2DF5C1677 CRC64;
MKPCQKMEGN LEKEDEPKPE EEPKPEEKPE EGQEPEEEEK SEETFRERLI RSLQDFQEDI
HNRHLSSDDL FRDVEELDEI RKVRNKLIVT RWKANRSHPY PYLM
